糖尿病黄斑水肿的治疗现状被引量：9

The Treatment of Diabetic Macular Edema

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摘要糖尿病黄斑水肿是由于高血糖所引起的眼部并发症,是造成糖尿病患者视力严重损害的原因之一。DME是一种多因素引起的复杂的病理过程,传统的治疗方法主要是黄斑部激光治疗。早期糖尿病视网膜病变研究组认为激光治疗对于临床有意义的黄斑水肿是有效的。近年来,DME治疗方法有了迅速进展,如手术治疗、眼内注射药物治疗。其中新型的眼内注射药物已成为伴有中心视力下降的DME一线治疗。 Diabetic macular edema（DME）,a serious eye complication caused by hyperglycemia,is one of the main causes of visual impairment in diabetic patients .DME is a complex pathological process caused by multiple factors.Conventional treatment is mainly based on laser photocoagulation.The study on early treatment for diabetic retinopathy showed that macular laser photocoagulation was beneficial for eyes with clinically significant macular edema .The treatment for DME is rapidly evolving in recent years ,such as surgi-cal treatment,intraocular pharmacotherapy.New drugs,given by intraocular injection,have become first line treatment for DME with loss of vision.

作者刘莉莉黄敏丽

机构地区柳州市工人医院眼科广西医科大学第一附属医院眼科

出处《医学综述》 2015年第15期2786-2789,共4页 Medical Recapitulate

关键词糖尿病糖尿病黄斑水肿激光治疗药物治疗手术 Diabetes Diabetic macular edema Laser photocoagulation Drug therapy Surgery

分类号 R774.5 [医药卫生—眼科] R587.2 [医药卫生—内分泌]

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1Klein R,Klein BE,Moss SE,et al.The Wisconsin Epidemiologic Study of Diabetic Retinopathy:XVII.The 14-year incidence and progression of diabetic retinopathy and associated risk factors in type 1 diabetes[J].Ophthalmology,1998,105(10):1801-1815.
2Matsuda S,Tam T,Sinqh RP,et al.The impact of metabolic parameters on clinical response to VEGF inhibitors for diabetic macular edema[J].Diabetes Complications,2014,28(2):166-170.
3No authors listed.Photocoagulation for diabetic macular edema.Early Treatment Diabetic Retinopathy Study report No 1.Early Treatment Diabetic Retinopathy Study research group[J].Arch Ophthalmol,1985,103(2):796-1806.
4Lavinsky D,Cardillo JA,Melo LA Jr,et al.Randomized clinical trialevaluating m ETDRS versus normal or high-density micropulse photocoagulation for diabetic macular edema[J].Invest Ophthalmol Vis Sci,2011,52(7):4314-4323.
5Vujosevic S,Bottega E,Casciano M,et al.Microperimetry and fundus autofluorescence in diabetic macular edema:subthreshold micropulse diode laser versus modified early treatment diabetic retinopathy study laser photocoagulation[J].Retina,2010,30(6):908-916.
6Muqit MM,Gray JC,Marcellino GR,et al.Barely visible 10 millisecond pascal laser photocoagulation for diabetic macular edema:observations of clinical effet and burn localization[J].Am Ophthalmol,2010,149(6):979-980.
7Gillies MC,Simpson JM,Gaston C,et al.Five-year results of a randomized trial with open-label extension of triamcinolone acetonide for refractory diabetic macular edema[J].Ophthalmology,2009,116(11):2182-2187.
8Beck RW,Edwards AR,Aiello LP,et al.Three-year follow-up of a randomized trial comparing focal/grid photocoagulation and intravitreal triamcinolone for diabetic macular edema[J].Arch Ophthalmol,2009,127(3):245-251.
9Elman MJ,Aiello LP,Beck RW,et al.Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema[J].Ophthalmology,2010,117(6):1064-1077.
10Elman MJ,Bressler NM,Qin H,et al.Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema[J].Ophthalmology,2011,118(4):609-614.