摘要
目的分析妊娠期合并梅毒感染患者不良妊娠结果及影响因素。方法选择2011年6月~2014年6月在我院确诊的妊娠期合并梅毒感染患者156例,计算不良妊娠结果发生率,并对不良妊娠结果相关影响因素进行分析。结果 1整体不良妊娠结果发生率为49.4%（77/156）。2不良妊娠结果发生在年龄、户籍地点（本市、外市）、婚姻状态（已婚、未婚）、经济水平（较好、一般、较差）及产次（初产、经产）等因素的比较中,差异无统计学意义（P〉0.05）,在首次检出梅毒时孕龄（≤12周,13~28周,≥29周）、梅毒感染分期（隐性,一/二期）、患者受教育程度、抗梅毒治疗（是/否）等因素的比较中,差异有统计学意义（P〈0.05）。3Logistic回归分析显示,首次检出梅毒时孕龄（OR=6.304）、梅毒分期（OR=5.553）、受教育程度（OR=1.378）、抗梅毒治疗（OR=0.417）为影响抗梅毒治疗的独立相关因素（P〈0.05）,其中首次检出梅毒时的孕龄、梅毒分期、受教育程度为危险因素（OR〉1.000）,抗梅毒治疗为保护性因素（OR〈1.000）。结论实际工作中应充分重视妊娠合并梅毒患者的早期检查、规范化治疗,改善妊娠梅毒患者的妊娠结果。
Objective To analyze the adverse pregnancy outcomes and influencing factors of pregnancy patients with syphilis. Methods A total of 156 cases of pregnancy patients with syphilis from June 2011 to June 2014 in our hospital were selected. The occurrence rate of adverse pregnancy outcomes and the influencing factors of adverse pregnancy outcomes was analyzed. Results 1The total occurrence rate of adverse pregnancy outcomes was 49.4%（77/156）. 2The differences of adverse pregnancy outcomes in the elements of age, family register（local, outlander）, marital status（married, singlehood）, economic level（well, general, poor）, parity（primiparity, multiparity） had no statistically significant（P〉0.05）. The differences of adverse pregnancy outcomes in the elements of the gestation age of syphilis detection for the first time（≤12 weeks,13-28 weeks, ≥29 weeks）, syphilis infection installment（recessiveness, the first/second phase）, education level, syphilis resistant treatment（yes/no） were statistically significant（P〈0.05）. 3According to the Logistic multivariate regression analysis, the gestation age of syphilis detection for the first time（OR=6.304）, syphilis infection installment（OR=5.553）, level of education（OR=1.378）, syphilis resistant treatment（OR=0.417） were the independent associated factors of syphilis resistant treatment（P〈0.05）; The gestation age of syphilis detection for the first time, syphilis infection installment, level of education were the risk factors of adverse pregnancy outcomes（OR〉1.000）,the syphilis resistant treatment was the protective factor of adverse pregnancy outcomes（OR〈1.000）. Conclusion It is essential to pay attention to the early detection, standardized treatment of pregnancy patients with syphilis, and take relevant measures to improve the pregnancy outcomes.
出处
《中国现代医生》
2015年第18期76-79,共4页
China Modern Doctor
关键词
妊娠合并梅毒
不良妊娠结果
影响因素
Pregnancy combined with syphilis
Adverse pregnancy outcomes
Influence factor
