摘要
艾滋病确证检测最常用的方法是免疫印迹试验，如果确证结果不是阴性，但又不满足阳性判定标准，则判定为HIV抗体不确定，约4％～20％的样品经过初筛复测阳性后，确证结果为HIV抗体不确定，不同地区差异较大。不确定者多来自无偿献血者、孕产妇等健康群体，条带的类型、数量对临床诊断有重要意义。影响不确定结果的因素复杂且尚不清楚。不确定者的随访依从性较差，转归以实验室出现非特异性反应为主，且与不确定标本的S／CO比值有关。对于HIV抗体不确定的标本，需结合实验室检测、流行病学调查结果、辅助诊断等进行综合分析和判断。
Western blot is the most commonly used method for HIV antibody test. The resuh of the sample is indeterminate if the result is not negative and positive criterion is not met. 4% - 20% of samples which are positive in screening test are indeterminate, and the result of different regions is quite different. The indeterminate sampies come from unpaid blood donors, pregnant women and other health groups. Type and number of indetermi- nation bands are very important for clinical diagnosis. Factors of indetermination are complex and not clear. Follow-up compliance is poor, and outcomes of indetermination are based on nonspeeific reactions, which are related to S/CO ratio. Laboratory tests, epidemiological findings, subsidiary diagnosis should be combined in order to analyze HIV antibody indeterminate specimen.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2015年第9期978-980,共3页
The Chinese Journal of Dermatovenereology
基金
上海市嘉定区卫生科研项目
流行病学学科(GW01)
关键词
HIV抗体
免疫印迹实验
不确定
Human immunodeficiency virus antibody
Western blot
Indetermination
