摘要
目的 探讨脓毒症、严重脓毒症及脓毒性休克患儿血清白蛋白水平与预后的相关性.方法 选取南阳市第一人民医院收治的142例患儿作为研究对象,其中脓毒症50例,严重脓毒症48例,脓毒性休克44例,对三组患儿均在纳入研究之后24h检测血清白蛋白,观察并对比各组患儿预后及低白蛋白血症发生情况.结果 脓毒症组30例（60.0％）患儿发生低白蛋白血症,严重脓毒症组和脓毒性休克组分别为41例（85.4％）和44例（100.0％）,各组患儿低白蛋白血症发生率比较差异有统计学意义（P＜0.05）;且各组低白蛋白血症患儿病死率、存活率比较差异有统计学意义（P＜0.05）,患儿PCIS评分、病死率与血清白蛋白浓度分别呈正相关和负相关（P＜0.05）.结论 严重脓毒症与脓毒性休克患儿的低白蛋白血症发病率明显高于脓毒症患儿发病率,患儿的血清白蛋白水平与其预后具有密切相关性.
Objective To investigate the correlation of serum albumin level with prognosis in children with sepsis,severe sepsis and septic shock.Methods One hundred and forty-two patients were selected as the research objects,there were 50 cases of sepsis,48 cases of severe sepsis,44 cases of septic shock.Serum albumin were detected after inclusion in the study within 24 h.And the incidence of hypoalbuminemia and patient＇ s prognosis in each group were observed and compared.Results There were 30 cases （60.0%） of hypoalbuminemia in sepsis group,and 41 cases （85.4%） and 44 cases （100%） in severe sepsis and septic shock group.There was significant difference in the incidence of hypoalbuminemia among the three groups（P 〈 0.05）.The fatality rate and survival rate among the three groups had significant differences （P 〈 0.05）.Children＇ s PCIS score was positively correlated with the levels of albumin,and the fatality rate was negatively correlated with the levels of albumin （P 〈 0.05）.Conclusions The incidence of hypoalbuminemia in children with severe sepsis and septic shock is significantly higher than that in the patients with sepsis.There is close correlation of the level of serum albumin in children with its prognosis.
出处
《中国实用医刊》
2015年第18期62-63,共2页
Chinese Journal of Practical Medicine
