摘要
目的探讨红细胞分布宽度(RDW)对重症肺炎患者预后的评估价值。方法选择101例重症肺炎患者,记录其RDW、超敏C反应蛋白(hs-CRP)、降钙素原(PCT)、CURB-65评分及28 d转归情况。分析存活组与死亡组、RDW正常组与RDW升高组间RDW、hs-CRP、PCT、CURB-65评分的差异,并评估上述指标对重症肺炎预后的预测能力。结果死亡组的PCT、RDW及CURB-65评分显著高于存活组(P<0.05),两组间hsCRP差异无统计学意义(P>0.05)。RDW升高组的年龄、RDW及CURB-65评分显著高于RDW正常组(P<0.05)。RDW预测重症肺炎患者死亡的ROC曲线下面积均大于PCT、hs-CRP及CURB-65评分(P<0.05),其对重症肺炎患者死亡的最佳预测值为14.85,该值具有较高的敏感度(0.931)和特异度(0.778)。结论 RDW有助于判断重症肺炎的病情严重程度,具有良好的预后预测价值。
Objective To investigate the prognostic value of red cell distribution width （RDW） in severe pneu- monia patients. Methods A total of 101 cases of severe pneumonia were enrolled. RDW, hypersensitive C - reactive protein （hs -CRP） , procalcitonin （PCT） and CURB -65 score were measured, and the 28 -day outcomes of the above parameters were recorded. RDW, hs - CRP, PCT levels and CURB - 65 score were compared between survivors and non - survivors, patients with high - RDW and those with normal - RDW. The prognostic value of RDW in severe pneumonia was assessed by the ROC curve. Results Non - survivors had higher PCT, RDW and CURB - 65 score than survivors （ P 〈 0. 05 ）, while HS - CRP level did not differ significantly between non - survivors and survivors （ P 〉 0. 05 ）. In the meantime, age, RDW and CURB - 65 score in the high - RDW group were significantly higher than those in the normal - RDW group （ P 〈 0.05 ）. In ROC analysis, the AUC of RDW predicting death of patients with severe pneumonia was lar- ger than that of PCT, HS - CRP and CURB - 65 score （ P 〈 0. 05 ）. The cut - off value of RDW for prognosis of severe pneumonia was 14. 85, with high sensitivity （0. 931 ） and high specificity （0. 778）. Conclusion RDW is helpful in as- sessing severity of severe pneumonia, and has important prognostic value.
出处
《广东医学》
CAS
北大核心
2015年第15期2350-2352,共3页
Guangdong Medical Journal
基金
国家自然科学基金资助项目(编号:81300012)
关键词
红细胞分布宽度
重症肺炎
预后
red cell distribution width
severe pneumonia
prognosis
