摘要
目的 探讨抗生素导致患儿严重不良反应情况和临床表现。方法 本次医学研究选择我院儿科2013年1月-2015年1月收治的1 031名儿童患者为观察对象,其中,120例患儿抗生素治疗后出现各种不良反应症状,回顾分析患者不良反应症状的发生部位、临床表现以及药物类型。结果 皮肤系统不良反应发生率较高,而免疫系统不良反应发生率则相对较低,且不同机体系统抗生素治疗后不良反应发生率对比具有统计学差异（P〈0.05）。同时,大部分患者为静脉途径给药,且不良反应发生时间主要集中于首次给药后,以及给药后30 min内。结论 患儿接受抗生素治疗后,常易发生皮肤、神经、消化、呼吸、循环以及免疫系统不良反应症状,因而需要对患者给药途径和类型进行适当选择。
Objective To investigate the cause of antibiotics in children with serious adverse reactions and clinical manifestations. Methods The medical research to select between treated from January 2013 to January 2015 in our hospital pediatric patients 1 031 children observed object,wherein a variety of adverse symptoms after 120 cases of children with antibiotic treatment,retrospective analysis of patients with poor site reactions occur symptoms,clinical manifestations and drug types. Results Skin higher incidence of adverse reactions,and immune system incidence of adverse reactions were relatively low,and the different body systems after antibiotic treatment incidence of adverse reactions contrast had statistical y significant difference（P〈0.05）.At the same time,most patients intravenous routes of administration,and the incidence of adverse reactions after the first time focused on the administration, as wel as within 30 min after dosing. Conclusion The patients received antibiotic treatment,often prone skin,nervous,digestive,respiratory symptoms of adverse reactions,circulation and immune system,and thus the need for the patient and the type of route of administration is appropriately selected.
出处
《中国卫生标准管理》
2015年第25期121-122,共2页
China Health Standard Management
关键词
抗生素
严重不良反应
临床分析
Antibiotic
Serious adverse reactions
Clinical analysis
