摘要
目的：观察腔镜术后联合不同药物治疗子宫内膜异位症的临床疗效。方法选取入医院治疗的子宫内膜异位症患者80例作为研究对象,均行腹腔镜手术,采用数字随机表将患者分为对照组和观察组,对照组术后取孕激素治疗,观察组术后取促性腺激素释放激素（ GnRH-a）治疗,观察治疗前、治疗后6个月生殖激素水平,随访12～15个月记录两组复发率及术后1年妊娠率。结果观察组治疗6个月 FSH、E2、LH 分别为（2.35±0.9）U/L、（94.35±21.63）ng/L、（2.74±1.01）U/L,均明显低于对照组,差异有统计学意义（P〈0.05）。随访12~15个月,观察组妊娠率为30.0%,明显高于对照组的10.0%,差异有统计学意义（P〈0.05）。结论腹腔镜术后取GnRH-a治疗子宫内膜异位症,可降低生殖激素水平,提高妊娠率。
Objective To observe the clinical effect of laparoscopic surgery combined with different drugs on endo-metriosis. Methods Eighty patients with endometriosis admitted were chosen as the research objects, they were all given laparoscopic surgery and divided into the control group and the observation group by the digital random table. The control group was given the therapy of progestin, the observation group was given the therapy of gonadotropin-releasing hormone （ GnRH-a） . And then the reproductive hormone levels of pretreatment and post-treatment of 6 months were observed, and the two groups’ recurrence rate and pregnancy rate after 1 year postoperatively was recorded. Results After 6 months’ treatment, FSH、E2、LH of the observation group respectively was（2. 35 ± 0. 9） U/L,（94. 35 ± 21. 63） ng/L,（2. 74 ± 1. 01 ） U/L, which were significantly lower than those of the control group, and the differences were significant （ P 〈0. 05 ） . With 12 to 15 months ’ follow-up, the pregnancy rate of the observation group was 30. 0%, which was significantly higher than 10. 0% of the control group, the difference was significant （P〈0. 05）. Conclusions GnRH-a in treatment of endometriosis after laparoscopic surgery can reduce the levels of reproductive hormone and improve the rate of pregnancy.
出处
《中国实用医刊》
2015年第20期70-72,共3页
Chinese Journal of Practical Medicine
关键词
子宫内膜异位症
腹腔镜手术
妊娠率
GnRH-a
Endometriosis
Laparoscopic surgery
GnRH-a
Rate of pregnancy
