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老年肺结核应用T细胞斑点检验诊断临床价值 被引量:3

Clinical value of T cell spot test in the diagnosis of pulmonary tuberculosis in old patients
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摘要 目的通过对红细胞沉降率、结核抗体测定、痰结核杆菌涂片检查以及结核感染T细胞检测4种检查方法的比较,探讨结核感染T细胞斑点试验诊断老年人肺结核的应用价值。方法 2012年1月-2013年12月收治的肺结核病老年患者中随机抽取77例作为试验组,再选择志愿作为对照组的21名非肺结核病老年患者,分别对2组进行红细胞沉降率、结核抗体测定、痰结核杆菌涂片检查以及结核感染T细胞检测,对比记录4种方法检测效果。结果结核感染T细胞检测灵敏度达94.81%,特异度为100.00%,检测效果明显优于红细胞沉降率检测、结核抗体测定和痰结核杆菌涂片检查,差异有统计学意义(P<0.01)。结论结核感染T细胞斑点试验诊断老年人肺结核的检测效果显著,可明显提高诊断准确度,值得临床推广。 Objective To investigate the value in the old people by tuberculosis infection T cell spot test, by comparing the four methods of red cell sedimentation rate, tuberculosis antibody, Mycobacterium tuberculosis in sputum - smear and tuberculosis in- fection T cell detection. Methods 77 pulmonary tuberculosis patients, since January 2012 to December 2013, and 21 cases of non - tuberculosis patients were respectively selected as the experiment group and the control group, which were respectively in- spected about red cell sedimentation rate, tuberculosis antibody, Mycobacterium tuberculosis in sputum - smear and T cell spot test. Results The detection sensitivity of T - cell spot test reached 94.81%, and the specificity reached 100.00%, which was significantly better than that of the red cell sedimentation rate, tuberculosis antibody and Mycobacterium tuberculosis in sputum - smear. The differences were statistically significant ( P 〈 0.01 ). Conclusion The detection effect of T - cell spot test in the diagnosis of old people tuberculosis infection is remarkable, and it can improve the accuracy of diagnosis and is worthy of clinical promotion.
出处 《中国卫生检验杂志》 CAS 2015年第18期3091-3092,共2页 Chinese Journal of Health Laboratory Technology
关键词 结核感染T细胞检测 老年人肺结核 灵敏度 特异度 Pulmonary tuberculosis T - cell spot test Elderly pulmonary tuberculosis Sensitivity Specificity
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