摘要
镁基金属材料具有生物可降解性、优异的生物活性和一定抑制细菌能力。本文在超声微弧氧化电解液添加Ag NO3,获得载银生物涂层,不仅可以缓解镁基材料降解过快,而且可以预防植入前期的感染问题。本实验在电解液中添加0.03 g/L、0.05 g/L、0.08 g/L的Ag NO3为实验组,在纯镁表面制备含Ag量不同的涂层与大肠杆菌和金黄色葡萄球菌共同培养,检测抗菌性。结果表明:不添加银的微弧氧化涂层没有抗菌性,当电解液中Ag NO3添加量为0.03 g/L时获得的涂层有抗菌作用,当Ag NO3添加量超过0.05 g/L,获得的涂层对金黄色葡萄球菌和大肠杆菌均具有强抗菌性能。
Magnesium-based metal material possesses biodegradable property,excellent biological activity and certain antibacterial ability. Adding Ag NO3 in the micro-arc oxidation electrolyte to obtain biological silver coating may not only ease the too fast degradation of magnesium based materials,but also prevent the early-implant infection. Pure magnesium micro-arc oxidation coating as the control group,the electro-lyte added with 0. 03 g/L,0. 05 g/L,0. 08 g/L of Ag NO3 as experimental group,were co-cultured with Escherichia coli and Staphylococcus aureus to detect their antimicrobial properties. The results showed that the pure magnesium micro-arc oxidation coating has no antimicrobial properties. The electrolyte added with 0. 03 g/L Ag NO3 showed an antibacterial effect,that added with more than 0. 05 g/L Ag NO3 showed strong antibacterial action on Staphylococcus aureus and Escherichia coli.
出处
《中国体视学与图像分析》
2015年第2期128-135,共8页
Chinese Journal of Stereology and Image Analysis
基金
国家自然科学基金(31370979)
黑龙江省高校创新团队建设计划项目
生物医用材料及其表面改性(2012TD010)
关键词
纯镁
微弧氧化
银
抗菌性能
pure magnesium
micro-arc oxidation
silver
antibacterial properties
