摘要
目的探讨新生儿外周静脉置入中心静脉导管（PICC）相关性感染的影响因素,以降低PICC导管相关性感染发生率。方法回顾性分析2012年6月-2014年12月414例接受PICC的新生儿临床资料,对新生儿PICC相关性感染的危险因素进行单因素和多因素logistic回归分析,采用SPSS16软件对数据进行统计分析。结果 414例新生儿经PICC发生导管相关性感染24例,感染发生率为5.8%;感染新生儿中检出病原菌24株,其中肺炎克雷伯菌12株占50.0%,凝固酶阴性葡萄球菌8株占33.3%,真菌4株占16.7%;导管执行地点、是否计划拔管、穿刺时间、导管堵管、穿刺次数与导管相关性感染有关,为其主要影响因素;导管执行地点（OR=1.702,95%CI：1.439～3.716）、是否计划拔管（OR=2.162,95%CI：1.682～4.902）、穿刺时间（OR=2.386,95%CI：2.251～5.392）、导管堵管（OR=1.381,95%CI：1.298～3.979）、穿刺次数（OR=1.402,95%CI：1.372～4.592）等因素为PICC导管相关性感染的高危因素。结论新生儿PICC导管相关性感染的影响因素繁多,宜对上述高危因素进行预防控制,以减少新生儿PICC相关性感染的发生。
OBJECTIVE To study the influencing factors of neonatal PICC related infections ,so as to reduce the in‐cidence of catheter related infections .METHODS From Jul .2012 to Dec .2014 ,the clinical data of 414 patients who underwent PICC newborns were retrospectively analyzed and statistical analysis of the data was performed by SPSS16 .Single factor analysis and multiple logistic regression analysis was carried out to find risk factors for neo‐natal PICC catheter related infections .RESULTS Totally 24 cases of occurred neonatal catheter related infections and the infection rate was 5 .8% .24 strains of pathogens were isolated from the infected newborns ,including 12 strains of K lebsiella pneumoniae （50 .0% ） ,8 strains of coagulase negative Staphylococcus （33 .3% ） ,and 4 strains of fungi （16 .7% ） .Catheter sites ,whether planned to receive extubation ,puncture time ,catheter bloc‐king ,frequency of puncture were proved to be related to catheter infections .Catheter sites （OR=1 .702 ,95%CI：1 .439-3 .716） ,and whether planned to drawing out the catheter （OR=2 .162 ,95% CI：1 .682-4 .902） ,the puncture time （OR=2 .386 ,95% CI：2 .251-5 .392） ,catheter blocking （OR=1 .381 ,95% CI：1 .298 -3 .979） , frequency of puncture （OR=1 .402 ,95% CI：1 .372-4 .592） were proved to be high‐risk factors for catheter‐re‐lated infections .CONCLUSION Many factors influence the neonatal PICC catheter‐related infections .Prevention measures should be taken to control these high‐risk factors so that the infection rate can be reduced .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第20期4757-4758,4763,共3页
Chinese Journal of Nosocomiology
基金
浙江省医药卫生一般研究计划(B类)基金资助项目(2013KYB249)
