摘要
中医学在防治肿瘤性疾病方面具有独特的疗效,中药的安全性、有效性、低毒性,使之成为现阶段研究抗肿瘤药物的热点。查阅近年来国内外具有代表性的文献,对中药复方、中药单体作用人肺腺癌A549细胞的实验研究结果进行分析归纳,发现很多中药复方及其中药单体被证实对A549细胞产生一定的影响,如诱导A549细胞凋亡和抑制A549细胞增殖,但具体的作用机制尚需深入研究。
Traditional Chinese medicine(TCM) has a unique efficacy in the prevention and treatment of tumor diseases.The safety,efficacy and low toxicity of Chinese medicine,make it become the current research hotspot of antitumor drugs.Traditional Chinese medicine is a rich source of cardiovascular medicine,particular those with antitumor.Refer to the typical literatures at home and abroad in recent years,this article gave some analysis and induction of human lung adenocarcinoma A549 cells treatment with Chinese medicine and Chinese medicine monomer.A lot of traditional Chinese medicine compound and its Chinese medicine monomer was proved to have influence on the A549 cells,such as inducing apoptosis of A549 cells and inhibiting proliferation of A549 cells,but further investigations were required to understand the chemical basis and the exact mechanism.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2015年第10期3601-3606,共6页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81202628)~~
关键词
中药
肺癌
A549细胞
Traditional Chinese medicine
Lung cancer
A549 cells