摘要
逍遥散具有明确的抗抑郁作用,但是其抗抑郁有效成分及其作用机制尚不清楚。从作用到成分、成分到机制2条途径,归纳总结了逍遥散中的抗抑郁有效成分以及这些成分发挥抗抑郁作用的可能机制,进一步确证了逍遥散作为经典抗抑郁古方所具有的多层次、多途径、多靶点等特点。
The antidepressive effect of Xiaoyaosan is obvious, however, the active ingredients with potential antidepressive activity and their mechanism remain unclear. In this paper, by two ways of the effects to active ingredients and the active ingredients to mechanism, the antidepressive active ingredients and their mechanism of Xiaoyaosan are summarized. Xiaoyaosan as a classic antidepressant Chinese prescription is further confirmed with many advantages, such as multi-level, multi-channel, multi-target, and so on.
出处
《中草药》
CAS
CSCD
北大核心
2015年第20期3109-3116,共8页
Chinese Traditional and Herbal Drugs
基金
国家国际科技合作项目(2011DFA32630)
"重大新药创制"科技重大专项(2012ZX09103201-035)
山西省科技攻关项目(20140313008-14)
山西省科技基础条件平台建设项目(2014091022)
关键词
逍遥散
抗抑郁
槲皮素
甘草苷
柴胡皂苷
芍药苷
阿魏酸
姜黄素
Xiaoyaosan
antidepression
quercetin
liquiritin
saikoside
paeoniflorin
ferulic acid
curcumin
