摘要
目的:评价定西市疑似预防接种异常反应(Adverse Event Following Immunization,AEFI)监测系统运行情况。方法:采用Excel 2003对公元2007至2013年定西市AEFI监测数据和接种率监测数据进行分析,了解AEFI报告率、AEFI发生时间、AEFI临床症状分布情况及报告及时性。结果:2007至2013年定西市AEFI报告率呈逐年上升趋势,由2007年的1.97/10万剂次升高到247.44/10万剂次;AEFI监测灵敏度逐年提高,48小时内报告率为99.53%,48小时内调查率为96.84%,调查报告上传率25.53%;97.1%的AEFI发生于接种疫苗后3天内,临床症状分布以发热/红肿/硬结为主,分别占74.43%、16.22%和7.62%,其他所占比重均较低。结论:2007至2013年定西市AEFI监测系统运转良好,监测数据质量较高,基本能够反映疫苗安全性的真实水平;部分年份监测敏感度很低,一定程度上影响到监测数据整体质量,应探讨合适的管理方法,帮助维持AEFI监测系统高效运转。
Objective： To evaluate surveillance system operation of Adverse Event Following Immunization （AE- FI） in Ding＇xi. Methods： AEFI surveillance data and vaccination rate surveillance data of Dingxi from 2007 to 2013 were analyzed with Excel 2003, in order to investigate AEFI reporting rate, AEFI incidence time, clinical symptoms distribution of reported AEFI, and timeliness of reporting. Results： AEFI reporting rate was raising year by year from 2007 to 2013, it raised from 1.97/100000 doses to 247.44/100000 doses; AEFI reproting sensitivity increased year by year, The reporting rate was 99.53% within 48 hours, the survey rate was 96.84% within 48 hours of AEFI and the report upload rate was 25.53%; 97.1% of AEFI reaction occurs within the first three days after being reported. Clinical symptoms distributions were mainly fever/red/induration, accounting for 74.43%, 16.22% and 7.62%, while others were lower. Conclusion： The surveillance system of AEFI operates well in the period from 2007 to 2013 in Dingxi. The actual level of vaccination safety could be reflected from the high quality surveillance data. But the reported sensitivity decreased dramatically in some year, and the quality of surveillance data would be affected. Proper management methods should be explored to maintain high operation of AEFI surveillance system.
出处
《西部中医药》
2015年第9期70-74,共5页
Western Journal of Traditional Chinese Medicine
