摘要
目的:比较研究不同后下时间银翘散汤剂体内抗甲型流感病毒的作用。方法:通过探讨不同后下时间煎煮银翘散汤剂对甲型流感病毒A/PR8/34(H1N1)感染小鼠死亡的保护作用、肺指数作用及肺组织病理组织学检查的药效差异,从而选择银翘散后下饮片的最佳煎煮时间。结果:从药效结果而言,不同后下时间煎煮的银翘散汤剂以薄荷、荆芥后下3min汤剂具有较好的抗甲型流感病毒作用。结论:应充分尊重中药传统煎煮方法的特殊要求,并结合临床经验,对于银翘散解表方剂用传统煎煮法以薄荷、荆芥后下煎煮3min较好。
Objective： To comprehensively compare the effects of Yinqiao Powder against influenza a virus in body during the cooking process with peppermint and fineleaf schizonepeta herb decocted later. Methods： Through studying on the death-protection effect of Yinqiao Powder decocted later at different time on influenza a virus A/PR8/34（H1N1） infected mice and pharmacodynamic action contrast of lung index and pulmonary histopathology to choose the best decocting time for the prepared drug in pieces of Yinqiao Powder to be decocted later. Results： The pharmacological results demonstrated that, among the different times of later decoction process for Yinqiao Powder, the anti influenza a virus effect of Yinqiao Powder with peppermint and fineleaf schizonepeta herb decocted later in 3min was better. Conclusion： Some special requirements of traditional decoction methods should be followed. The clinical experience demonstrates that, the best decoction method for Yinqiao Powder is the traditional decoction methods with peppermint and fineleaf schizonepeta herb decocted later in 3min.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2015年第11期4048-4052,共5页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81503216)
江苏省"六大人才高峰"第九批项目(No.WS-029)~~
关键词
银翘散
汤剂
后下
抗病毒
薄荷
荆芥
煎煮方法
Yinqiao Powder
Decoction
Decocted later
Antiviral
Peppermint
Fineleaf schizonepeta herb
Decocting method
