摘要
橡胶在药品包装材料中被广泛用于制造各种塞类。在方便药物运输、贮存的同时也有许多对药物潜在的不良影响,如对药物的吸附、微粒污染、穿刺落屑和化学反应等。本文从药用胶塞的配方成分入手,介绍了其与药品的相容性问题。
Rubber is widely used as stoppers in the pharmaceutical packaging material system. Although it is convenient for the transport and storage of medicines, there are many adverse effects to the medicines, such as the absorption of medicines, particle contamination, chips fall when punctured the stopper and chemical reactions with medicines etc. This article introduced the ingredients of rubber stoppers for pharmaceutical use and sketched its compatibility with the pharmaceutical products.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2015年第12期1366-1371,共6页
Chinese Journal of Pharmaceuticals
关键词
药用胶塞
药品相容性
浸出物
可提取物
综述
rubber stoppers for pharmaceutical
compatibility
leachable
extractable
review