期刊文献+

肿瘤抑素的应用及研究进展

The application and research progress of Tumstatin
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摘要 肿瘤的生长需要新生血管来为其提供充足的营养物质和氧气,因此通过抑制血管的生成能够抑制肿瘤的生长。在所有来源于Ⅳ型胶原的内源性血管生成抑制剂中,肿瘤抑素的研究最广泛。肿瘤抑素具有抑制血管内皮细胞增殖、诱导内皮细胞凋亡、直接抑制肿瘤细胞增殖,促进肿瘤细胞凋亡等多种功能。本文就肿瘤抑素的研究现状进行综述。 Growth of tumor need new blood vessel to meet the demand for adequate oxygen and nutri- ents. Inhibiting the formation of blood vessel can inhibit growth of tumor. In all of the endogenous angiogenesis in- hibitors deriving from the type IV collagen. Study of tumstatin is the most widely. Tumstatin can inhibit endothelial proliferation and induce the apoptosis of endothelial cell. This article reviews the research status of the tumstatin.
出处 《实用肿瘤学杂志》 CAS 2015年第6期549-552,共4页 Practical Oncology Journal
基金 黑龙江省卫生厅科研课题(2010-030)
关键词 肿瘤抑素 凋亡 增殖 血管 Tumstatin Apoptosis Proliferation Blood
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参考文献23

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