摘要
研究祛斑保健品的急性毒性和遗传毒性。采用小鼠急性经口毒性试验、Ames试验、小鼠骨髓嗜多染红细胞微核试验和小鼠精子畸形试验对祛斑保健品进行常规安全性实验分析。急性经口毒性实验结果表明,雌雄小鼠经灌胃给予祛斑保健品,其最大耐受剂量(MTD)均大于15g/kg,该样品属无毒级。Ames试验、微核试验和精子畸形试验结果均为阴性。祛斑保健品在人体推荐摄入剂量3.6g/d范围内是安全可靠的。
To study the acute toxicity and genotoxicity of Quban health products. Acute toxicity test, ames test,micronucleus test of bone marrow PCE cell in mice, spermabnormality test of mice were used. The oral acute toxicity study revealed that the maximal tolerance dose（MTD） of Quban health products was greater than 15g/kg in mice. The results of ames test, micronucleus test and sperm shape abnormality test were all negative. Quban health products showed no acute toxicity and genotoxicity in this study. Thus, Quban health products is safe at the daily recommended dose（3.6g/person/day）.
出处
《食品与发酵科技》
CAS
2015年第6期47-49,104,共4页
Food and Fermentation Science & Technology
