摘要
目的探讨医院妇科门诊患者生殖道分泌物的病原学与耐药性,为临床上治疗生殖道感染选用合理的抗菌药物、缩短治疗时间提供可靠依据。方法回顾性分析2013年5月-2014年5月在医院妇科门诊就诊的患者260例,统计所有患者生殖道分泌物常规检查结果,分析病原菌分布并进行药敏试验;采用SPSS19.0软件进行统计分析。结果 260例感染患者中Ⅰ度清洁10例占3.85%,Ⅱ度清洁51例占9.62%,Ⅲ度清洁132例占50.77%,Ⅳ度清洁67例占25.77%;共检出病原体309株,其中原核108株,真核生物201株,革兰阴性菌55株,以大肠埃希菌为主,革兰阳性菌78株,以无乳链球菌为主,真菌68株,以假丝酵母菌为主;大肠埃希菌对阿米卡星、厄他培南、亚胺培南、头孢替坦敏感率>90.00%,对舒巴坦、磺胺甲噁唑/甲氧苄啶的敏感性较差均<40.00%;无乳链球菌对替加环素、舒巴坦、青霉素、亚胺培南、万古霉素敏感率100.00%,对四环素敏感性较差为4.76%;原核病原体以支原体属和衣原体属为主,其中支原体属对交沙霉素、多西环素敏感率>95.00%,衣原体属对交沙霉素、阿奇霉素、四环素敏感率>97.00%。结论医院妇科门诊患者感染以真核生物为主,原核生物次之,以支原体属、衣原体属、假丝酵母菌属、大肠埃希菌、无乳链球菌检出率最高;临床上应合理选用抗菌药物,降低耐药株的产生,缩短治疗过程。
OBJECTIVE To explore the etiology of genital tract secretions of the gynecology clinic patients and analyze the drug resistance so as to reasonably use antibiotics for clinical treatment of genital tract infections and shorten the treatment time.METHODS A total of 260 patients who were treated in the gynecological outpatient department from May 2013 to May 2014 were retrospectively analyzed,the results of conventional examination of the genital tract secretions were taken for statistics,the distribution of the pathogens was observed,the drug susceptibility testing was carried out,and the statistical analysis was performed with the use of SPSS19.0software.RESULTS Of 260 patients with infections,10（3.85%）were treated with degreeⅠ cleaning,51（9.62%）were treated with degreeⅡ cleaning,132（50.77%）were treated with degree Ⅲ cleaning,and 67（25.77%）were treated with degreeⅣcleaning.Totally 309 strains of pathogens were isolated,including 108 strains of pronuclei,201 strains of eucaryon,55 strains of gram-negative bacteria,78 strains of gram-positive bacteria,and 68 strains of fungi;the Escherichia coli was the predominant species of gram-negative bacteria;the Streptococcus agalactiae was dominant among the gram-positive bacteria;the Candida wad dominant among the fungi.The drug susceptibility rates of the E.coli to amikacin,ertapenem,imipenem,and cefotetan were more than 90.00%,and the drug susceptibility rates to sulbactam and sulfamethoxazole-trimethoprim were less than 40.00%.The drug susceptibility rates of the S.agalactiaeto tigecycline,sulbactam,penicillin,imipenem,and vancomycin were 100.00%,and the drug susceptibility rate to tetracycline was 4.76%.The Mycoplasmaand Chlamydia were dominant among the prokaryotic pathogens;the drug susceptibility rates of the Mycoplasmato josamycin and doxycycline were more than 95.00%;the drug susceptibility rates of the Chlamydiato josamycin,azithromycin,and tetracycline were more than 97.00%.CONCLUSIONThe eucaryon is dominant among the pathogens causing the infections in the patients of gynecological outpatient department,followed by the pronuclei.The isolation rates of Mycoplasma,Chlamydia,Candida,E.coli,and S.agalactiae are the highest.It is necessary for the hospital to reasonably use antibiotics so as to reduce the drug-resistant strains and shorten the treatment course.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第2期407-409,共3页
Chinese Journal of Nosocomiology
基金
辽宁省科学技术计划基金资助项目(2007225007)
关键词
妇科门诊
分泌物
病原学
耐药性
Gynecology clinic
Secretion
Etiology
Drug resistance
