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直肠神经内分泌肿瘤的诊断与治疗(附14例报告) 被引量:2

Diagnosis and treatment of rectal neuroendocrine tumor: a report of 14 cases
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摘要 目的:分析直肠神经内分泌肿瘤(neuroendocrine tumor,NET)的临床诊断及治疗。方法 :对14例直肠NET临床及病理资料进行回顾分析并随访。结果:瘤体直径<1 cm 8例,≥1 cm且<2 cm 4例,2 cm 1例,3 cm 1例。瘤体直径<2 cm的12例,实施经肛门局部切除术3例,内镜下黏膜切除术9例。瘤体直径≥2 cm的2例,行低位直肠前切除术。13例获访者无死亡病例。结论:直肠NET生物学行为低度恶性,瘤体直径<2 cm的一般不侵犯肌层,也很少转移,大多数病例可经肛门局部切除或行内镜黏膜切除术治愈。 Objective To analyze the diagnosis and treatment in rectal neuroendocrine tumor. Methods The clinical and pathological data of 14 cases with rectal neuroendocrine tumor were analyzed retrospectively. Results Tumor diameter was〈1 cm in 8 cases,≥1 cm and〈2 cm in 4 cases and that in other 2 cases was 2 cm and 3 cm respectively. The treat-ment for 12 cases with tumor〈2 cm of diameter was transanal local resection in 3 cases and endoscopic mucosal resection in 9 cases. Low anterior resection was performed in 2 cases with tumor ≥2 cm of diameter. Thirteen patients were followed and all survived. Conclusions The results of our study showed that the biological behavior of rectal neruoendocrine tumor is low malignant potential. The lesions with〈2 cm of diameter do not invade muscularis propria and rarely metastasize. Most of the patients could be cured by local resection including transanal local excision and endoscopic mucosal resection.
作者 陈利文
出处 《外科理论与实践》 2015年第6期515-517,共3页 Journal of Surgery Concepts & Practice
关键词 直肠肿瘤 直肠神经内分泌肿瘤 治疗 Rectal neoplasms Rectal neuroendocrine tumor Treatment
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参考文献8

  • 1Bosnmn FT, Carnerio F, Hruban RH, et al. WHO classifi- cation of tumours of the digestive system[M]. Lyon: IARC Press,2010:195-334.
  • 2laggard MA, O'Connell JB, Ko CY. Updated population- based review of carcinoid tumors[J]. Ann Surg,2004,240(1):117-122.
  • 3Modlin IM, Sandor A. An analysis of 8305 cases of carci- noid tumors[J]. Cancer,1997,79(4):813-829.
  • 4Naunheim KS, Zeitels J, Kaplan EL, et al. Rectal carcinoid tumors: treatment and prognosis [J]. Surgery, 1983,94 (4): 670-676.
  • 5Son HJ, Sohn DK, Hong CW, et al. Factors associated with complete local excision of small rectal carcinoid tu- mor[J]. Int J Colorectal Dis,2013,28(1):57-61.
  • 6Kim YJ, Lee SK, Cheon IH, et al. Efficacy of endoscopic resection for small rectal carcinoid: a retrospective study [J]. Gastroenterology,2008,51 (3): 174-180.
  • 7阮荣蔚,王实,刘永军,陶亚利,俞江平,朱舒文.内镜超声和内镜黏膜下剥离诊治直肠类癌31例[J].中国微创外科杂志,2012,12(12):1063-1066. 被引量:11
  • 8Woodside KJ, Townsend CM Jr, Mark Evers B. Current management of gastrointestinal carcinoid tumors[J]. J Gas- trointest Surg,2004,8(6):742-756.

二级参考文献16

  • 1王向东,王志强,黄启阳,李闻,王永华,刘迎娣,孟江云,杜红,杨云生.直肠类癌的内镜超声图像特征[J].中华消化内镜杂志,2005,22(2):98-100. 被引量:24
  • 2Fahy BN,Tang LH,Klimstra D,et al. Carcinoid of the rectum riskstratification ( CaRRS ) : a strategy for preoperative outcomeassessment. Ann Surg Oncol, 2007 ,14(2) :396 -404.
  • 3Kinoshita T,Kanehira E,Omura K,et al. Transanal endoscopicmicrosurgery in the treatment of rectal carcinoid tumor. SurgEndosc,2007,21(6) :970 -974.
  • 4Shen EF, Aronott ID, Plevris J, et al. Endoscpic ultrasonography inthe diagnosis and management of suspected upper gastrointestinalsubmucosal tumors. Br J Surg,2002,89(2) :231 -235.
  • 5Soga J. Early-stage carcinoids o. the gastrointestinal tract : ananalysis of 1914 reported cases. Cancer, 2005 , 103 ( 8 ) : 1587 -1595.
  • 6Kiyonori K,Tomoe K, Shigeru Y, et al. Indications of endoscopicpolypectomy for rectal carcinoid tumors and clinical usefulness ofendoscopic ultrasonography. Dis Colon Rectum, 2005 , 48 ( 2 ):285 -291.
  • 7Jung IS, Ryu CB, Kim JO, et al. Rectal carcinoid treated by EMR.Gastrointest Endosc,2003,58(2) :253.
  • 8Kwaan MR, Goldberg JE, Bleday R. Rectal carcinoid tumors:review of results after endoscopic and surgical therapy. Arch Surg,2008,143(5) :471 -475.
  • 9Konishi T, Watanabe T, Kishimoto J, et al. Prognosis and riskfactors of metastasis in colorectal carcinoids : results of a nationwideregistry over 15 yeare. Gut,2007 ,56(6) :863 - 868.
  • 10Moon SH, Hwang JH, Sohn DK,et al. Endoscopic submucosaldissection for rectal neuroendocrine ( carcinoid ) tumors. JLaparoendosc Adv Surg Tech A,2011,21(8) : 695 -699.

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