摘要
目的胆囊癌发病症状无特异性，早期诊断困难，本研究分析2005—2008年兰州市胆囊癌的发病流行特征，为胆囊癌的预防控制提供科学依据。方法收集甘肃省肿瘤登记处2005—2008年已公布恶性肿瘤发病病例资料，统计和分析胆囊癌粗发病率和构成比、年龄别发病率、中标率和世标率、年平均增长速度等指标。结果2005—2008年兰州市胆囊癌新发病例共469例，男181例，女288例。总体发病率为6．70／10万，中标率为5．60／10万，世标率为7．69／10万，累积率（0-74岁）0．96％，构成比3．20％，居全部恶性肿瘤发病顺位第7位。男性发病率为5．04／10万，中标率为4．25／10万，世标率为5．95／10万，累积率（0～74岁）0．73％，构成比2．10％，居全部恶性肿瘤发病顺位第9位。女性发病率为8．41／10万，中标率为6．97／10万，世标率为9．46／10万，累积率（0-74岁）1．21％，构成比4．70％，居全部恶性肿瘤发病顺位第5位。女性发病率明显高于男性。发病率随年龄增高而升高，≥45岁人群胆囊癌发病率急剧升高，75～岁组人群发病率达高峰。2005—2008年间兰州市胆囊癌发病率呈增高趋势，每年以12．97％的速度增长。结论兰州市胆囊癌发病率高于全国水平，已成为威胁兰州市居民健康的主要恶性肿瘤之一，应加强防治研究，以期有效控制胆囊癌高发现状。
OBJECTIVE To analyze the epidemiological pattern of gallbladder cancer in Lanzhou, so as to provide the evidence for prevention and control of gallbladder cancer. METHODS The registered cancer data of new cases in 2005 --2008 was collected from Gansu Cancer Registry. The indexes, including crude incidence, age-specific incidence, age- standardized rate by Chinese population, age-standardized rate by world population and average annual growth rate were calculated. RESULTS Totally 469 new diagnosed cases of gallbladder cancer were reported（181 in male,288 in female）. The crude incidence of gallbladder cancer in Lanzhou in 2005--2008 was 6.70/105 , the age-standardized rates by Chinese standard population was 5.60/105 and age-standardized rate by world standard population was 7.69/105 with the cumulative incidence rate（0-74 age years old） of 0.96%. It accounted for 3.20% of all cancer cases ranked the seventh. The crude incidence of gallbladder cancer for male was 5.04/10^5 , the age-standardized rate by Chinese standard population was 4.25/105 and age-standardized rate by world standard population was 5.95/105 with the cumulative incidence rate（0- 74 age years old） of 0.73G. It accounted for 2.10% of all cancer cases ranked the ninth. The crude incidence of gallblad- der cancer for female was 8.41/105 , the age-standardized rate by Chinese standard population was 6. 97/105 and age standardized rate by world standard population was 9.46/105 with the cumulative incidence rate （0--74 age years old） of 1.21% . It accounted for 4.70% of all cancer cases ranked the fifth. Female incidence was higher than that of male. The incidence of gallbladder cancer increased with age worth and dramatic increased after 45 years old, reached peak at the age of 75 years old. The incidence of gallbladder cancer was increased rapidly during 2005--2008 in Lanzhou and the average growth rate was 12.97% per annum. CONCLUSIONS Incidence of gallbladder cancer is higher than the average level of China and is one of the major threats to the health in Lanzhou. Control of gallbladder cancer is still need to be strengthened in Lanzhou.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2015年第21期1654-1657,共4页
Chinese Journal of Cancer Prevention and Treatment
关键词
胆囊肿瘤
发病率
流行病学
兰州
gallbladder neoplasms
incidence
epidemiology
Lanzhou
