摘要
目的:探讨中西医结合治疗高血压脑出血并发肺部感染患者血清炎症因子水平的临床观察。方法:纳入的70例高血压脑出血并发肺部感染患者根据随机数字表法随机分为中西医组和西医组各35例。中西医组给予中西医结合治疗,西医组给予常规西药治疗。疗程均为14 d。结果:中西医组治疗总有效率(85.71%)较西医组(62.86%)高,且有统计学意义(P<0.05);中西医组治疗后症状积分较治疗前减少(P<0.05),且低于西医组(P<0.05);中西医组治疗后体征积分较治疗前减少(P<0.05),且低于西医组(P<0.05);中西医组治疗后血清hs-CRP、IL-6、TNF-α较治疗前减少(P<0.05),且低于西医组(P<0.05);中西医组治疗后收缩压、舒张压较治疗前下降(P<0.05),且低于西医组(P<0.05);而中西医组治疗后血氧饱和度较治疗前上升(P<0.05),且高于西医组(P<0.05);中西医组平均住院时间短于西医组(P<0.05);两组用药均未见严重不良反应。结论:中西医结合治疗高血压脑出血并发肺部感染患者可降低血清炎症因子水平,改善炎症状态,且疗效明显。
Objective： To investigate the effect of combined treatment of traditional Chinese and Western Medicine on serum inflammatory factors in patients with hypertensive cerebral hemorrhage complicated with pulmonary infection. Methods： 70 cases of hypertensive cerebral hemorrhage complicated with pulmonary infection were randomly divided into Chinese and Western medicine group（ n = 35） and Western medicine group（ n = 35） according to the random number table method. The Chinese and Western medicine group was treated with integrated Chinese and Western medicine,western medicine group was treated with routine western medicine. The course of treatment was 14 d. Results： The total effective rate（ 85.71%） was higher than that of Western medicine group（ 62. 86%）,and it had statistical significance（ P〈0. 05）; The symptom score after treatment was decreased（ P〈0.05）,and lower than that in western medicine group（ P〈0.05）; Western medicine group after treatment syndrome scores less than before treatment（ P〈0. 05）,and lower than the western medicine group（ P〈0.05）; hs-CRP,TNF-α and IL-6 were decreased in the treatment of TCM and Western medicine（ P〈0.05）,and the treatment group was lower than that in western medicine group（ P〈0.05）; After treatment,the systolic blood pressure and diastolic blood pressure were decreased（ P〈0.05）,and lower than that in western medicine group（ P〈0.05）; The blood oxygen saturation was higher than that of Western medicine group（ P〈0.05）; The average length of hospital stay was shorter than that of Western medicine group（ P〈0. 05）; the two groups had no serious side effects. Conclusion： Combined Chinese and Western medicine treatment of hypertensive cerebral hemorrhage complicated with pulmonary infection can reduce the level of serum inflammatory factors,improve the inflammatory state,and the effect is obvious.
出处
《中华中医药学刊》
CAS
北大核心
2016年第2期510-512,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
中西医
高血压脑出血
肺部感染
血清炎症因子
疗效
Chinese and Western medicine
hypertensive cerebral hemorrhage
pulmonary infection
serum inflammatory factors
curative effect
