摘要
目的:研究硫辛酸治疗糖尿病周围神经病变临床效果及安全性。方法:将40例糖尿病周围神经病变病人,随机分为对照组和治疗组,治疗组在常规治疗基础上采用硫辛酸进行治疗,对照组患者在常规治疗基础上给予维生素B1、B12治疗,随访3个月。采用多伦多临床评分系统比较患者治疗前后症状分、反射分、感觉分及总分;观察2组的临床总评分的改善状况。结果:两组患者治疗前后症状分、反射分、感觉分、总分比较差异均有统计学意义(P<0.05);治疗后组间各积分比较,差异均有统计学意义(P<0.05,P<0.01)。结论:运用硫辛酸治疗糖尿病周围神经病变疗效肯定、安全性高。
Objective: To study the efficacy and safety of lipoic acid in the treatment of diabetic peripheral neuropathy. Methods: 40 cases of patients with diabetic peripheral neuropathy were randomly divided into control group and treatment group,treatment group was given lipoic acid treatment in addition to conventional treatment,and control group was given vitamin B1,B12 treatment in addition to conventional treatment. The patients were followed up for 3 months. The Toronto Clinical Scoring Systems was used to compare the symptom score,reflection score,feeling score and total score of the two groups before and after the treatment. Observe the improvement of the clinical total scores of the two groups. Results: The differences between the symptom score,reflection score,feeling score and total score of the two groups before and after the treatment were statistically significant( P < 0. 05); The differences of the scores after the treatment were statistically significant( P < 0. 05,P < 0. 01). Conclusion: Using lipoic acid to treat diabetic peripheral neuropathy has remarkable effect and high safety.
出处
《数理医药学杂志》
2016年第3期348-349,共2页
Journal of Mathematical Medicine
