摘要
目的:比较运用河车路行罐配合擦法与西药治疗糖尿病后抑郁症的疗效差异。方法:将216例患者随机分为观察组和对照组,每组108例。观察组采用河车路行罐配合擦法治疗,隔日1次,6次为一疗程,疗程间休息4天,共治疗2个疗程;对照组口服盐酸氟西汀胶囊治疗,每日1次,连续服用4周。分别于治疗前、治疗结束、治疗后1个半月随访,采用汉密尔顿抑郁量表(HAMD)、自评抑郁量表(SDS)、中医证候评分进行评定;治疗前、治疗后检测空腹血糖(GLU);随访时检测糖化血红蛋白(HbA1c)。结果:观察组总有效率为90.9%(90/99),优于对照组的73.7%(70/95,P<0.05)。治疗后,观察组与对照组HAMD、SDS、中医证候评分均下降(均P<0.05);观察组治疗结束及随访中医证候评分较对照组低(均P<0.05)。观察组患者HbA1c、GLU控制较平稳,且较治疗前有所下降,但两组间比较差异无统计学意义(P>0.05)。结论:河车路理论指导下的中医治疗方法比西药盐酸氟西汀分散片口服对糖尿病后抑郁症综合疗效更优,且不良反应更少。
Objective To compare the efficacy between moving cupping at Hechelu combined with rubbing method and western medication for depression of diabetes mellitus（DM）.Methods Two hundred and sixteen patients were randomly divided into an observation group and a control group,108 cases in each group.Patients in the observation group were treated with moving cupping at Hechelucombined with rubbing method,once every other day;six treatments were considered as one course,and totally two courses were given with an interval of 4 days between courses.Patients in the control group were treated with oral administration of fluoxetine hydrochloride capsules,once a day for consecutive 4 weeks.The Hamilton depression scale（HAMD）,self-rating depression scale（SDS）and TCM symptom score were measured before treatment,after the treatment and in followup visit one and a half months after treatment.The fasting blood glucose was tested before and after treatment.The glycosylated hemoglobin（HbA1c）was tested in the follow-up visit.Results The total effective rate was 90.9%（90/99）in the observation group,which was superior to 73.7%（70/95）in the control group（P〈0.05）.After the treatment,HAMD,SDS and TCM symptom scores were all reduced apparently in the observation group and the control group（all P〈0.05）.After the treatment and the follow-up visit,the TCM symptom score in the observation group was lower than that in the control group（P〈0.05）.The levels of HbA1 cand GLU were stable in the observation group,and were decreased compared with those before treatment;but the difference between the two groups was not significant（P〉0.05）.Conclusion The Hechelutheory-based TCM treatment has better efficacy for depression of diabetes mellitus than fluoxetine hydrochloride capsule,which has less adverse effects.
出处
《中国针灸》
CAS
CSCD
北大核心
2016年第3期245-249,共5页
Chinese Acupuncture & Moxibustion
基金
四川省科技厅科技支撑计划项目:2013SZ0116
关键词
糖尿病
抑郁
河车路
拔罐
盐酸氟西汀
随机对照试验
diabetes mellitus（DM）
depression
Hechelu
cupping therapy
fluoxertine hydrochloride
randomized controlled trial（RCT）
