摘要
目的调查北京市怀柔区糖尿病患者应用降糖药物的现状。方法向2014年11月10日至2015年2月10日北京市怀柔区16家社区卫生服务中心管理的900例糖尿病患者发放对降糖药物应用及相关知识的调查问卷，对患者的用药种类、用药依从性及药物效果进行统计，采用多因素logistic回归分析影响患者使用降糖药物的因素。结果回收有效调查问卷899份。单一用药的患者中，二甲双胍使用率最高（23．7％，213／899），两种及两种以上联合用药的患者中，二甲双胍和阿卡波糖（11．8％，106／899）、二甲双胍和格列奈类胰岛素促泌剂（17．1％，154／899）的使用率较高。患者中有65．9％（592／899）遵医嘱立即使用降糖药物，32．2％（290／899）没有遵医嘱立即用药或延缓用药，1．9％（17／899）未使用降糖药物。Logistic回归分析显示，影响患者使用降糖药物的因素有用药种类（t=-4．351，P=0．000）、认为药物会产生不良反应（t=6．999，P=0．000）、认识到糖尿病对健康的危害（t=-10．969，P=0．000）和医生的建议（t=-3．352，P=0．001）。结论糖尿病患者使用降糖药物的种类选择和联合用药方式与糖尿病指南推荐用药基本一致，部分糖尿病患者未能遵医嘱使用降糖药物，降糖药物的药品种类、认为药物会产生不良反应、是否认识到糖尿病对健康的危害和医生的建议是影响糖尿病患者用药的因素。
Objective To investigate the awareness and administration of antidiabetic drugs in patients with diabetes in Huairou district of Beijing. Methods A questionnaire survey on knowledge and administration of antidiabetic drugs were conducted in 900 diabetic patients from 16 communities in Huairou district of Beijing from November 2014 to February 2015. The related factors influencing antidiabetic drug use were analyzed with logistic regression method. Results A total of 899 questionnaires were recovered. Results showed that the rate of metformin single use was the highest （23.7%, 213/899 ）, the rate of combination use of metformin and acarbose was 11.8% （ 106/899 ） , and that of mefformin and glipizide was 17.1% （154/899）. Survey showed that 65. 9% （592/899） patients were compliant immediately for antidiabetic agents, 32.2% （290/899） were not immediately compliant, 1.9% （17/899） did not use antidiabetic agents. Logistic regression analysis showed that the factors affecting the use of antidiabetic agents were the types of medication （ t = - 4.351, P = 0. 000） , adverse effects of drugs （t = 6. 999, P = 0. 000）, awareness of diabetes to health hazard （t = -10. 969, P = 0. 000） and the doctor＇s recommendation （t = - 3. 352, P = 0. 001 ）. Conclusion The results showed that the administration of antidiabetic drugs in diabetic patients from Huairou district is basically followed the recommendation by 2013 edition of type 2 diabetes guidelines and the compliance rate of medication need to be further raised.
出处
《中华全科医师杂志》
2016年第2期114-117,共4页
Chinese Journal of General Practitioners
关键词
糖尿病
降血糖药
认知
Diabetes mellitus
Hypoglycemic agents
Cognition
