摘要
自2008年以来,手足口病(HFMD)疫情在我国多个地区流行,给我国公共卫生局面带来巨大挑战,而肠道病毒71型(EV71)是引起手足口病的主要病原体之一。微小RNA(micro RNA)作为一种非编码单链RNA分子,通过调节病毒复制和基因表达在多种病毒感染性疾病的发生、发展和预后中发挥重要作用。本文就mi RNA分子在EV71型HFMD诊断、治疗中的作用和研究进展作以综述。
Hand, foot and mouth disease(HFMD) is widely spread in China since 2008 and gives challenge to public health, and Enterovirus 71(EV71)is one of the main pathogens of HFMD. As a noncoding, single stranded RNA, the mi RNA(micro RNA) plays important roles in virus infected diseases through regulating virus replication and gene expression. This paper reviewed about the application of mi RNA in the diagnosis and treatment of HFMD with EV71 infection.
出处
《中华实验和临床感染病杂志(电子版)》
CAS
2016年第1期10-12,共3页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
基金
广东省医学科研基金(No.A2014519)
深圳市新发传染病重点专科基金(No.201161)
深圳市科技计划项目(No.JCYJ20140411112047888)
关键词
微小RNA
肠道病毒71型
手足口病
mi RNA
Enterovirus 71(EV71)
Hand
mouth and foot disease(HFMD)