摘要
目的:分析Th17T淋巴细胞浸润及相关细胞因子在免疫性前列腺炎组织中的表达水平。方法:将60只小鼠分为2组,研究组和对照组,造模成功后,取前列腺组织,分别进行免疫组化和PCR检测Th17T淋巴细胞浸润及其相关细胞因子表达情况。结果:前列腺炎组小鼠前列腺组织中CD4+,CD8+,IL-17+T淋巴细胞计数显著高于对照组(P<0.01)。前列腺炎组小鼠前列腺组织中IL-17、IL-23p19、IL-23p40 mRNA的表达水平显著高于对照组(P<0.01)。结论:免疫性前列腺炎组织Th17T淋巴细胞浸润及其相关细胞因子表达显著升高。
Objective： To analyze Th17 T lymphocytes infiltration and associated cytokines expression in immunity prostatitis tissue. Method： 60 mouses were divided into study group and control group. Study group was made immunity prostatitis model. After model,Th17 T lymphocytes infiltration and associated cytokines expression were detected. Result： CD4 ＋,CD8 ＋,IL-17 ＋ T lymphocytes infiltration in immunity prostatitis tissue increased apparently（ P〈0. 01）. IL-17、IL-23p19、IL-23p40 mRNA expression in immunity prostatitis tissue increased apparently（ P〈0. 01）. Conclusion： Th17 T lymphocytes infiltration and associated cytokines expression in immunity prostatitis tissue.
出处
《河北医学》
CAS
2016年第3期467-470,共4页
Hebei Medicine
基金
广东省自然科学自由申请项目
(编号:S2012010009126)
