摘要
目的:观察腹腔灌注复方苦参注射液及顺铂联合微波热疗治疗卵巢癌腹水患者的疗效及毒副反应。方法:将患者分为2组,研究组39例以915MHz型大功率微波腹部区域热疗联合复方苦参注射液及顺铂腹腔灌注。对照组39例行复方苦参注射液及顺铂腹腔灌注,未行腹部热疗。结果:全部患者均顺利完成治疗,研究组39例中完全缓解(CR)26例,部分缓解(PR)7例,有效(CR+PR)率为84.62%。对照组39例中CR 17例,PR 6例,有效率为58.98%。两组有效率比较,差异有显著性(P<0.05)。结论:915MHz型大功率微波腹部区域热疗联合复方苦参注射液及顺铂腹腔灌注治疗卵巢癌腹水,疗效较单纯腹腔灌注复方苦参注射液及顺铂疗效好,未增加毒副反应,提高了治疗效果。
Objective：To obsmwe the adverse reaction and intraperitoneal perfusion of matrine and cisplatin combined with microwave hyperthermia in the treatment of patients with ovarian cancer ascites. Methods：The patients were divided into 2 groups 39 cases in the study group were treated with 915MHz type high power microwave abdominal regional hyperthermia combined with compound Kushen injection and cisplatin intraperitoneal perfusion. In control group ,39 cases were treated by compound matrine injection and cisplatin intraperitoneal perfusion, no abdominal thermotherapy. Results：All patients were successfully completed treatment, in the study group complete remission（CR） in 26 cases,partial remission（PR） in 7 cases,effective（CR ＋ PR） was 84.62%. 39 cases in control group,CR 17 cases, PR 6 cases, efficiency of 58.98% （P 〈 0.05 ）. Conclusion： 915MHz type high power microwave abdominal regional hyperthermia combined with compound Kushen injection and cisplatin intraperitoneal chemotherapy in ovarian cancer ascites, effect of combined intraperitoneal perfusion of compound matrine injection and cisplatin has good cura- tive effect ,without increasing toxicity, improve the treatment effect.
出处
《现代肿瘤医学》
CAS
2016年第9期1443-1445,共3页
Journal of Modern Oncology
关键词
卵巢癌腹水
复方苦参注射液
顺铂
腹腔灌注
微波区域热疗
ovarian cancer, peffusion of compound matrine injection, cisplatin, ascites intraperitoneal, microwave re-gional hyperthermia
