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合并严重基础疾病的类风湿关节炎患者治疗策略分析

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摘要 目的:探讨合并严重基础疾病的类风湿关节炎患者的治疗策略。方法:选取我院2013年2月-2015年2月收治的17例合并严重基础疾病的类风湿关节炎患者的临床资料,分析该类患者的治疗策略。结果:12例患者病情不同程度缓解,4例患者因原发基础疾病不能耐受治疗失败,1例患者因原发病死亡。结论:活动期类风湿关节炎合并严重基础疾病患者,应该以治疗危及生命的基础疾病为主要目标,对于类风湿关节炎的治疗以改善病情,减轻症状为主,充分发挥风湿免疫科的专业知识,积极配合相关科室医生制定适宜的治疗方案,提高患者的生活质量。
作者 魏凯 闻进朝
出处 《医学理论与实践》 2016年第5期633-635,共3页 The Journal of Medical Theory and Practice
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  • 1Weasels JA,de Vries-Bonwstro JK,Heijmans BT,et al.Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nuclcetide polymorphisms in genes coding for folate parthway enzymes.Arthritis Rheum,2006,54:1087-1095.
  • 2Griffith S,Fisher J,Clarke S,et al.Do patients with rheumatoid arthritis established on methotrexate and folic acid 5 mg daily need to continue folic acid supplements long term? Rheumatology,2000,39:1102-1109.
  • 3Hoekstra M,van Ede A,Haagsma C,et al.Factors associated with toxicity,final dose,and efficacy of methotrexate in patients with rheumatoid arthritis.Ann Rheum Dis.2003,62:423-426.
  • 4Ortiz Z,Shea B,Suarez-Almazor M,et al.The efficacy of folic acid and folinic acid in reducing methotrexate gastrointestinal toxicity in rheumatoid arthritis:a Meta analysis of randomized controlled trials.J Rheumatol,1998,25:36-43.
  • 5Khanna D,Park G,Paulus H,et al.Reduction in efficacy of methotrexate by the use of folic acid:post hoc analysis from two randomized controlled studies.Arthritis Rheum,2005,52:3030-3038.
  • 6Visser K,Katchamart W,Loza E,et al.Multinational evidencebased recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis:integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E initiative.Ann Rheum Dis,2009,68:1086.
  • 7Quimn MA, Conaghan PC, Emery P. The therapeutic oppcoeeh of early interwartion for theunatoid arthritis: what is the evi- dence? Rheunatology (oxrlrd) [J]. 2001 Nov, 40 (11): 1211 - 1220.
  • 8Anderson JJ, wells A, Verhoeven AC, et al. Faetors preel: cting vesponse to treatment in thevmato: darthr: tis the impor- tance of disease duration. Arthritis Rheum [ J ]. 2000 Jan, 43 (1): 22-29.
  • 9Hyrich KL, Watson KD, Lunt M, et al. Changes in disease characterisics and response rates among patients in the United Kingdom starting anti - tumour necrosis factor therapy for rheu matoid arthritis between 2001 and 2008 [ J ]. Rheumatology (Oxford), 2011, 50 (1): 117-123.
  • 10Rahman MU, Buchanan J, Doyle MK, et al. Changes in pa- tient characteristics in anti - tumour necrosis factor clinical trails for rheumatoid arthritis ; results of an analysis of the literature o- ver the past 16 years [J]. ANN Rheum Dis, 2011, 70 (9) : 1631 - 1640.

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