摘要
目的观察替硝唑治疗加重型口腔感染的临床疗效。方法选取2014年6月至2015年6月收治的加重型口腔感染患者100例,采用随机数字表法分为研究组和对照组,各50例。研究组给予替硝唑治疗,对照组给予甲硝唑治疗,观察并比较两组临床疗效及不良反应发生情况。结果研究组总有效率为94.00%,显著高于对照组的74.00%(P<0.05);研究组患者的症状消失时间和伤口愈合时间均显著短于对照组(P<0.05);研究组恶心、呕吐、腹泻、便秘和头痛的发生率均显著低于对照组(P<0.05)。结论替硝唑治疗加重型口腔感染效果好、安全性高、实用性好,值得临床推广。
Objective To compare the clinical effectiveness of Tinidazole and metronidazole in the treatment of severe oral infection. Methods 100 cases of patients with exacerbation of oral infection in the hospital from June 2014 to June 2015 were selected and were randomly divided into the study group and the control group, 50 cases in each group. The study group was treated with tinidazole, while the control group was treated with metronidazole. The clinical efficacy and adverse reactions of the two groups were observed and compared. Results The total effective rate of the study group was 94. 00%, which was significantly higher than 74.00% of the control group（ P 〈 0. 05）. The symptoms disappear time and wound healing time of the study group were significantly shorter than those in the control group（ P 〈 0. 05）. The incidence of nausea, vomiting, diarrhea, constipation and headache in the study group was significantly less than that in the control group（ P 〈 0. 05）. Conclusion ： Tinidazole has good effect in the treatment of severe oral infection, with high safety and good effectiveness.
出处
《中国药业》
CAS
2016年第7期39-41,共3页
China Pharmaceuticals
关键词
替硝唑
甲硝唑
加重型口腔感染
临床疗效
tinidazole
metronidazole
severe oral infection
clinical efficacy
