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养血清脑颗粒联合地巴唑治疗血管性头痛随机平行对照研究 被引量:2

Yangxueqingnaokeli Joint Methimazole to Treat Vascular Headache Randomized Controlled Study
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摘要 [目的]观察养血清脑颗粒联合地巴唑治疗血管性头痛疗效。[方法]使用随机平行对照方法,将80例住院及门诊患者按抛硬币法简单随机分为两组。对照组40例尼莫地平,40mg/次,3次/d。治疗组40例养血清脑颗粒,4g/次,3次/d;地巴唑,20mg/次,3次/d。连续治疗28d为1疗程。观测临床症状、红细胞比容、纤维蛋白原、血浆黏度、全血比黏度、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈7例,显效15例,有效16例,无效2例,总有效率95.00%。对照组痊愈3例,显效9例,有效18例,无效10例,总有效率75.00%。治疗组疗效优于对照组(P<0.05)。血液流变学指标治疗组改善优于对照组(P<0.05)。[结论]养血清脑颗粒联合地巴唑治疗血管性头痛疗效满意,无严重不良反应,值得推广。 [Objective] To observe the clinical efficacy of yangxueqingnaokeli joint methimazole to treat the vascular headache.[Methods] Randomly devided 80 patients into two groups.the control group of 40 patients used nimodipine, 40mg/time, 3 times/d. And the treatment group of 40 patients used yangxueqingnaokeli, 4g/time, 3 times/d; methimazole, 20mg/time, 3 times/d. 28 d of continuous treatment for a course.to observe the clinical symptoms, hematocrit, fibrinogen, plasma viscosity, whole blood viscosity and adverse reactions. One course of treatment determined the efficacy. [Results] The treatment group cured 7 cases, 15 cases markedly, effective in 16 cases, and invalid 2 cases,the total efficiency was 95.00%. The control group cured 3 cases,9 cases markedly, effective in 18 cases, and invalid 10 cases,the total efficiency was 75.00%. The efficacy of treatment group was better than control group(P〈0.05). Blood rheology indexes improve treatment group is better than that of control group(P〈0.05). [Conclusion] Yangxueqingnaokeli joint methimazole to treat vascular headache,the treatment effect was satisfied, had no serious adverse reactions,was worth for promotion.
作者 陈湘勇
出处 《实用中医内科杂志》 2016年第4期68-70,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 血管性头痛 养血清脑颗粒 地巴唑 红细胞比容 纤维蛋白原 血浆黏度 全血比黏度 中西医结合治疗 随机平行对照研究 Vascular Headache Yangxueqingnaokeli Methimazole Hematocrit Fibrinogen Plasma Viscosity Whole Blood Viscosity Combination Therapy Randomized Controlled Study
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