摘要
血管内皮生长因子通过与其受体结合后特异性地促进内皮细胞有丝分裂和介导血管形成并增加血管通透性,也可介导肿瘤血管的形成,肿瘤细胞生长依赖新生血管的形成已经是肿瘤生物学上广为人知的一个方面,肿瘤新生血管在肿瘤的形成、进展、浸润和迁移中起着至关重要的作用。本文就近年来国内外有关VEGF及其受体在肿瘤血管生成方面的作用作一简要综述。
Vascular endothelial growth factor promotes endothelial cell mitosis and angiogenesis and increase vascular permeability,which can also mediate tumor angiogenesis,tumor cell growth depends on the formation of tumor biology. Tumor angiogenesis plays an important role in tumor formation,progression,invasion and migration. In this paper,the effects of VEGF and its receptor in tumor angiogenesis were reviewed.
出处
《中国优生与遗传杂志》
2016年第5期146-148,共3页
Chinese Journal of Birth Health & Heredity
基金
延安大学校级科研项目(No.YDQ2014-49)
