摘要
目的探讨高压氧辅助治疗脑膜瘤术后脑水肿的临床疗效。方法选取2010年1月至2014年1月收治的78例脑膜瘤术后脑水肿患者,按数字表法随机分成两组,每组39例。对照组采取常规抗感染、止血以及神经营养等基础对症治疗;观察组在对照组常规治疗的基础上,采用高压氧疗辅助治疗。观察两组患者的治疗效果以及脑水肿的相关量化评分情况。结果术后3 d两组患者脑水肿体积比较差异未见统计学意义;术后7 d观察组水肿体积显著小于对照组,且随着时间的推移这种差距逐渐扩大,差异有统计学意义(P<0.05)。治疗前,两组患者神经功能缺损情况评分、脑水肿分级评分、日常生活能力评分比较差异未见统计学意义,治疗后两组神经功能缺损情况评分、脑水肿分级评分均降低,日常生活能力评分均升高,且组间比较差异有统计学意义(P<0.05)。结论高压氧疗辅助治疗脑膜瘤能够显著改善患者的脑水肿情况,促进患者脑组织的康复,显著改善患者的生活质量,值得临床推广应用。
Objective To investigate the clinical effect of hyperbaric oxygen on adjunctive therapy for cerebral edema after meningioma operation. Methods From January 2010 to January 2014, 78 cases of cerebral edema after meningioma operation were randomly divided into two groups, with 39 cases in each group. The control group received foundational treatment such as conventional anti infection, hemostasis and neurotrophic treatment. The observation group received hyperbaric oxygen therapy based on the control group. The therapeutic effect and relevant quantitative of the cerebral edema between the two groups were ob- served. Results The volume of cerebral edema had no significant difference between the two groups 3 days after operation, and the edema volume of observation group was significantly less than that of control group 7 days after operation, and with the pas- sage of time the gap was gradually expanding, the differences were significant（ P 〈 0. 05 ）. Before the treatment, there was no significant difference between the two groups in neurological deficit, cerebral edema score or daily life ability score. The neuro- logical deficit, cerebral edema score decreased, and daily life ability score increased in both groups after treatment, and there were significant differences between the two groups （P 〈0. 05 ）. Conclusion Hyperbaric oxygen in adjunctive therapy for men- ingioma can significantly improve the symptom of cerebral edema, promote the rehabilitation of patients with brain tissue, signifi- cantly improve the quality of life, it is worthy of popularization and application in clinic.
出处
《临床医学》
CAS
2016年第5期19-21,共3页
Clinical Medicine
关键词
高压氧
脑膜瘤
脑水肿
疗效
Hyperbaric oxygen
Meningioma
Cerebral edema
Curative effect
