摘要
妊娠期高钙血症可对孕妇和胎儿的健康造成极大风险,临床上很少见,最常见的病因是原发性甲状旁腺功能亢进症( PHPT)。妊娠期PHPT的临床表现和生化指标改变不典型,诊断难度大,且治疗手段局限,处理原则尚无统一标准。准确评估患者病情对指导治疗有很大帮助,评估时需将妊娠期的钙磷代谢特点纳入考虑。重症患者首选孕中期手术切除病灶。
Hypercalcemia in pregnancy is a rare condition which brings considerable risks to mother and fetus. The most common cause is primary hyperparathyroidism(PHPT). The untypical symptoms and biochemical tests results add obstacles in the diagnosis of PHPT during pregnancy. The management is difficult, due to restrictions in choices of treatments and lack of clinical guidelines. Severity evaluation which takes consideration of calcium homeostasis during pregnancy is crucial for appropriate management. Parathyroidectomy during the second trimester is recommended for those with high serum calcium levels.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2016年第5期415-417,共3页
Chinese Journal of Endocrinology and Metabolism