摘要
糖尿病心脑血管并发症、糖尿病肾病、糖尿病视网膜病分别是目前糖尿病患者死亡、终末期肾病、成人致盲的主要原因。目前,关于糖尿病并发症的发病机制的研究主要集中于氧化应激与慢性炎症方面。此外,已有大量研究指出胆红素具有抗氧化及抗炎症作用。因此,胆红素与糖尿病并发症有着密切联系。
Cardiovascular disease ,diabetic nephropathy and diabetic retinopathy are common complications of diabetes ,and are the significant reason of cardiovascular mortality ,end-stage renal disease ,and blindness in adults patients with type 2 diabetes mellitus. At present, the researche on the pathogenesis of diabetic complications mainly focus on oxidative stress and chronic inflammation. In addition, a large number of studies have pointed out that bilirubin has antioxidant and anti-inflammatory effects. Therefore, bilirubin and diabetic complications are closely linked.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2016年第5期426-428,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病
并发症
胆红素
抗氧化作用
Diabetes mellitus
Complications
Bilirubin
Antioxidant effect