摘要
目的:观察五苓散加味对轮状病毒感染性腹泻患儿临床疗效及外周血T淋巴细胞亚群的影响。方法:选取80例轮状病毒感染性腹泻患儿作为研究对象,随机分为对照组和治疗组各40例,两组患儿均给予西医常规止泻、补液等对症治疗,治疗组在此基础上加用中药五苓散加味治疗,疗程为5 d,比较两组患儿临床疗效及外周血T淋巴细胞亚群水平变化。结果:治疗组与对照组患儿临床愈显率分别为95.0%、80.0%,治疗组患儿临床愈显率明显高于对照组(P<0.05);两组患儿治疗后CD3+、CD4+、CD8+及CD4+/CD8+水平较治疗前、同期对照组上述指标均有明显差异(P<0.05),具有统计学意义。结论:五苓散加味治疗小儿RV感染性腹泻疗效较高,其作用机制可能与改善机体免疫功能状态有关。
Objective： To observe the clinical effects of Supplemented Wuling Powder on Infants with rotavirus diarrhea and its influence on the T-lymphocyte subsets in the peripheral blood. Methods： Totally eighty infants with rotavirus diarrhea were selected as the study objects and randomized into control group and treatment group,with 40 cases in each group. Both groups were given conventional symptomatic western medicine treatment of stopping diarrhea and supplementing fluid,while treatment group were additionally given Chinese medicine of Supplemented Wuling Powder for the treatment,5 d as a treatment course. The clinical effects and the change of the level of T-lymphocyte subsets in the peripheral blood in the two groups were compared. Results： The curative and markedly effective rate was 95. 0% in treatment group,significantly higher than the 80. 0% in control group（ P 〈0. 05）. The levels of CD3＋,CD4＋,CD8＋and CD4＋/ CD8＋in both groups greatly changed after the treatment,and the above indicators between the two groups had significant difference（ P 〈 0. 05）. Conclusion： Supplemented Wuling Powder has high effective rate on infants with rotavirus diarrhea,whose mechanism may be related with the improvement of the body immunity.
出处
《河南中医》
2016年第5期766-767,共2页
Henan Traditional Chinese Medicine
关键词
小儿腹泻
五苓散
轮状病毒
《伤寒论》
张仲景
infantile diarrhea
Wuling Powder
rotavirus
Treatise on Cold Damage
Zhang Zhongjing
