手术与药物保守治疗甲状腺功能亢进的比较研究被引量：4

在线阅读下载PDF

导出

摘要目的探讨手术与药物保守治疗甲状腺功能亢进的临床效果。方法将来我院就诊的120例甲状腺功能亢进患者随机分为手术治疗组(观察组)与药物保守治疗组(对照组)各60例,观察组采取甲状腺大部切除术,而对照组采取药物保守治疗,比较2组在临床治疗效果、并发症及不良反应发生率方面的差异。结果与对照组比较,观察组总有效率更高,且并发症及不良反应发生率较对照组低,2组比较差异有统计学意义(P<0.05)。结论甲状腺大部切除术和药物保守治疗均是治疗甲状腺功能亢进的有效措施,但甲状腺大部切除术比采取药物保守治疗效果更为显著,其治疗的总有效率高、不良反应发生率低,患者恢复好,值得在临床上推广应用。

作者刘海峰

机构地区广灵县人民医院

出处《基层医学论坛》 2016年第18期2478-2479,共2页 The Medical Forum

关键词甲状腺功能亢进大部切除术药物保守治疗疗效比较

分类号 R581.1 [医药卫生—内分泌]

引文网络
相关文献

参考文献2

1曾芳芳,吴晞,刘红.甲状腺机能亢进症的药物治疗[J].上海医药,2012,33(6):4-6. 被引量：4
2刘恒超,袁超,陶新全,周翔,申勇.放射性^(131)碘治疗老年人甲亢的临床价值[J].实用全科医学,2005,3(6):524-524. 被引量：7

二级参考文献25

1陆志强;高鑫;林祥通.甲状腺功能亢进症[A]北京:人民卫生出版社,20091261-1266.
2Shiroozu A,Okamura K,Ikenoue H. Treatment of hyperthyroidism with a small single daily dose of methimazole[J].Journal of Clinical Endocrinology and Metabolism,1986,(01):125-128.
3Mashio Y,Beniko M,Ikota A. Treatment of hyperthyroidism with a small single daily dose of methimazole[J].Acta Endocrinologica(Copenh),1988,(01):139-144.
4Mashio Y,Beniko M,Matsuda A. Treatment of hyperthyroidism with a small single daily dose of methimazole:a prospective long-term follow-up study[J].Endocrine Journal,1997,(04):553-558.
5Nakamura H,Noh JY,Itoh K. Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease[J].Journal of Clinical Endocrinology and Metabolism,2007,(06):2157-2162.
6Konishi T,Okamoto Y,Ueda M. Drug discontinuation after treatment with minimum maintenance dose of an antithyroid drug in Graves' disease:a retrospective study on effects of treatment duration with minimum maintenance dose on lasting remission[J].Endocrine Journal,2011,(02):95-100.
7Shizume K. Long term antithyroid drug therapy for intractable cases of Graves' disease[J].Endocrinologia Japonica,1978,(04):377-379.
8Slingerland DW,Burrows BA. Long-term antithyroid treatment in hyperthyroidism[J].Journal of the American Medical Association,1979,(22):2408-2410.
9Lippe BM,Landaw EM,Kaplan SA. Hyperthyroidism in children treated with long term medical therapy:twenty-five percent remission every two years[J].Journal of Clinical Endocrinology and Metabolism,1987,(06):1241-1245.
10Azizi F,Ataie L,Hedayati M. Effect of long-term continuous methimazole treatment of hyperthyroidism:comparison with radioiodine[J].European Journal of Endocrinology,2005,(05):695-701.