摘要
体部立体定向放射治疗(stereotactic body radiotherapy,SBRT)成为医学上不能手术的早期非小细胞肺癌(non-small cell lung cancer,NSCLC)的标准治疗方式。近十年的临床证据表明SBRT替代手术治疗效果可观。由于毒副作用小,SBRT同样适用于肺功能差、患有某些严重并发症的老年患者。最近针对可手术早期NSCLC患者的对比研究中发现SBRT可能同样适用于这一群体,但这些可观的结果仍需要长期随访的前瞻性实验的验证。本文就SBRT治疗早期非小细胞肺癌的临床进展做一综述。
Stereotactic body radiotherapy（SBRT）represents a consolidated treatment option for patients with medi-cally inoperable early stage non - small cell lung cancer（NSCLC）. The clinical evidence accumulated in the past dec-ade supports its use as an alternative to surgery with comparable survival outcomes. Due to its limited toxicity,SBRT is also applicable to elderly patients with very poor baseline pulmonary function or other severe comorbidities. Recent comparative studies inoperable patients raised the issue of the possible use of SBRT also for this subgroup,with quite promising results that still should be fully confirmed by prospective trials with long - term follow - up. In this review, we discuss the research progress on treating early stage NSCLC with SBRT.
出处
《现代肿瘤医学》
CAS
2016年第16期2644-2647,共4页
Journal of Modern Oncology
基金
黑龙江省科技计划项目任务书(编号:GC04C30902)
关键词
体部立体定向放射治疗
SBRT
非小细胞肺癌
早期
SBRT
stereotactic body radiotherapy
SBRT
non - small cell lung cancer
early stage
