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CD4+CD25+调节性T细胞/辅助性T细胞17失衡在急性肺损伤小鼠中的作用 被引量:8

Effect of CD4 + CD25 + regulatory T cells and T helper type 17 cells in lipopolysaccharide-induced acute lung injury mice
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摘要 急性肺损伤(acutelunginjury,ALI)是感染、创伤等导致的急性难治性呼吸衰竭,尽管呼吸支持治疗已取得显著进步,但其病死率依然高达40%。ALI的发生和发展涉及到多种病理生理过程,目前认为失控的炎症反应是其发生的根本机制。辅助性T细胞17(Th17)和CIM+CD25+调节T细胞(Treg细胞)细胞是近几年才发现的CD4+T淋巴细胞亚群,其数量及功能的异常与感染性疾病的发生与发展密切相关。
出处 《中华急诊医学杂志》 CAS CSCD 北大核心 2016年第7期892-895,共4页 Chinese Journal of Emergency Medicine
基金 基金项目:湖北省卫生计生科研基金(WJ2015MB149)
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