摘要
目的评估石家庄地区输血传播HBV、HCV、HIV的残余风险。方法以石家庄地区2013年1月-2014年12月献血者ELISA筛查数据及其基本资料为基础,采用(WP/I)、(WP/LTR)数学模型分别评估重复献血者及初次献血者传播HBV、HCV、HIV的残余风险。结果 2013年1月-2014年12月石家庄地区献血者,经ELISA检测后输血传播HBV、HCV、HIV的残余风险分别为1∶28 714、1∶41 102、1∶601 506。结论本地区经ELISA检测后存在输血传播病毒残余风险,核酸检测技术(NAT)应用于血液筛查可降低输血传播HBV、HCV、HIV残余风险。
Objective To assess the residual risk of transfusion-transmitted hepatitis B virus（ HBV）,hepatitis C virus（ HCV）,human immunodeficiency virus（ HIV） in Shijiazhuang. Methods The evaluation results were based on the data of serological ELISA blood screening and the blood donors principal information from January 2013 to December 2014 in Shijiazhuang. The（ WP / I） and（ WP / LTR） mathematical models of risk assessment were performed to evaluate the HBV,HCV and HIV residual risk on the repeated and the first-time donors,respectively. Results The residual risk of transfusion-transmitted HBV,HCV,HIV of the donors after ELISA blood screening were 1∶28 714,1∶41 102 and 1∶601 506 in Shijiazhuang during January 2013-December 2014. Conclusion The residual risk of transfusion-transmitted infection existed after ELISA detection. Nucleic acid amplification techniques（ NAT） can reduce the residual risk of transfusion-transmitted HBV,HCV,HIV.
出处
《中国卫生检验杂志》
CAS
2016年第13期1939-1941,共3页
Chinese Journal of Health Laboratory Technology
基金
河北省卫计委指令性课题(ZL-20140122)
关键词
残余风险
乙型肝炎病毒
丙型肝炎病毒
艾滋病病毒
核酸检测技术
Residual risk
Hepatitis B virus
Hepatitis C virus
Human immunodeficiency virus
Nucleic acid amplification techniques
