摘要
目的：评价能谱 CT 多参数定量值在鉴别肺占位病变（直径＞0．5 cm）性质的应用价值。方法回顾性分析接受能谱 CT 双期增强扫描且经病理证实的肺占位病变58例，其中恶性组48例，良性组10例。分别测量动脉期（AP）和静脉期（VP）碘基图像上病灶和同层面主动脉的碘含量（IC），并计算两期病灶相对于主动脉的标准化碘浓度（NIC）及两期标准化碘浓度之差 ICD（ICD ＝NICvp-NICap）。测量50 keV、100 keV 单能量图像上病灶的 CT 值，并计算能量衰减曲线斜率，即 Hu（100keV-50keV）／Hu 50 keV。采用独立样本 t 检验的方法，比较良、恶性肺占位之间两期 NIC、曲线斜率及 ICD 的差异性。结果两期扫描中，恶性占位病变的两期 NIC、静脉期曲线斜率及 ICD 均显著高于良性占位病变（动、静脉期恶性占位病变组 NICap：0．180±0．051、NICvp：0．463±0．086、1．696±0．475，ICD：0．284±0．071；良性占位病变组 NICap：0．123±0．062、NICvp：0．290±0．119、1．169±0．582，ICD：0．166±0．073，），但动脉期良恶性肺占位病变曲线斜率差异无统计学意义。结论能谱 CT 双期增强扫描可以对良、恶性肺占位病变的性质进行鉴别，且具有一定的临床应用价值。
Objective To evaluate the application value with Energy Spectrum CT multi -parameter quanti-tative value in differentiating pulmonary occupying lesions （＆gt;0.5cm in diameter）.Methods Those were retrospec-tively analyzed on 58 cases in pulmonary occupying lesions performed spectrum dual -phase enhanced CT scan and confirmed by pathology,including malignant group 48 cases;10 cases of benign group.Iodine content（IC）was meas-ured in arterial phase（AP）and venous phase （VP）in iodine based on the image and the level of the aorta,and nor-malized iodine concentrations were calculated in the two phases lesions compared with aorta,and the difference between the two normalized iodine concentrations ICD （ICD =NICvp -NICap）.To measure the CT value of lesions on 50keV and 100keV energy image,and calculate the energy attenuation curve slope,namely ｜Hu （100 kev -50kev）/Hu50 ｜.The differences of NIC,curve slope,and ICD were compared between benign and malignant pulmonary occupying lesions using independent sample t test method.Results In two phase scan,NIC,curve slope of the venous phase and ICD in malignant group were significantly higher than the benign group,（NIC,curve slope of the venous phase and ICD of the malignant group：NICap：0.180 ±0.051,NICvp：0.463 ±0.086,1.696 ±0.475,ICD：0.284 ± 0.071;NIC,curve slope of the venous phase and ICD of the benign group：NICap：0.123 ±0.062,NICvp：0.290 ± 0.119,1.169 ±0.582,ICD：0.166 ±0.073,）,but there was no significant difference between the patients with benign and malignant lesions in curve slope of the arterial phase.Conclusion Energy spectrum CT dual -phase enhanced scan can differentiate the nature of benign and malignant pulmonary occupying lesions,and has certain clinical application value.
出处
《中国基层医药》
CAS
2016年第15期2358-2361,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
能谱CT
标准化碘浓度
能量衰减曲线
肺占位病变
Energy Spectrum CT
normalized iodine concentrations
energy attenuation curve slope
pulmonary occupying lesions
