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子宫解剖异常对IVF/ICSI鲜胚移植妊娠产科结局的影响

Effect of the abnormal uterine anatomy on the obstetric outcome of pregnant women with IVF/ICSI fresh embryo transfer
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摘要 目的:探讨子宫解剖异常对行体外受精/卵胞质内单精子注射(IVF/ICSI)鲜胚移植患者妊娠产科结局的影响。方法:回顾性分析79例子宫解剖异常的不孕患者的临床资料,按照子宫解剖异常的不同类别进行分组,选择同期子宫解剖形态正常的172例不孕症患者作为对照,比较各组的一般情况、内膜厚度、妊娠产科结局。结果:观察各组患者的年龄显著高于对照组,差异有统计学意义(P<0.05),组间不孕年限比较,子宫畸形组高于对照组,差异有统计学意义(P<0.05),组间体质量指数、月经第2天子宫内膜厚度、HCG日子宫内膜厚度、移植日子宫内膜厚度比较,差异均无统计学意义(P>0.05);子宫腺肌症组流产率显著高于对照组,差异有统计学意义(P<0.05);组间早期流产率、晚期流产率、早产率、低体质量儿率比较,差异均无统计学意义(P>0.05)。结论:子宫解剖异常可影响妊娠结局,子宫腺肌症增加流产率。 Objective To evaluate the influence of abnormal uterine on obstetric outcome of pregnancy after IVF/ICSI fresh em-bryo transfer.Method A retrospective study was conducted of 79 patients′clinical data as the study group,diagnosed with abnormal uterine,and grouping according to different categories of abnormal.In the mean time,172 infertile patients with normal uterine were enrolled as control group,and comparing basic factors,thickness of endometria and the obstetric outcome of pregnancy between dif-ferent groups.Results The age of study groups was higher significantly than control group,the difference was statistically significant (P 〈0.05),the duration of infertility of uterine malformation group was higher than control group,the difference was statistically significant (P 〈0.05).There was no statistically significant differences in BMI、endometrial of the second day menstruation、endom-etrial of HCG day、endometrial of embryo transfer day (P 〉0.05);The abortion rate of uterine adenomyosis group was higher signif-icantly than control,the difference was statistically significant (P 〈0.05);There was no statistically significant differences in early abortion rate、late abortion rate、preterm birth rate、low birth weight rate (P 〉0.05).Conclusion Abnormal uterine have effects on the outcome of pregnancy,uterine adenomyosis increase abortion rate.
出处 《吉林医学》 CAS 2016年第8期1916-1918,共3页 Jilin Medical Journal
关键词 子宫解剖异常 IVF/ICSI-ET 鲜胚移植 Abnormal uterine In vitro fertilization/intracytoplasmic sperm injection - embryo transfer(IVF/ICSI - ET) Fresh embryo transfer
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