摘要
术后认知功能障碍(postoperative cognitive dysfunction,POCD)是手术和麻醉后出现的一种中枢神经系统并发症,在老年患者中发病率较高。但是,POCD的确切机制目前仍不明确。近年来,越来越多的证据表明,全身麻醉药物作为术后认知功能障碍的影响因素之一,可对老年患者的认知功能产生广泛的影响。因此,对于麻醉药物影响认知功能机制的探讨,对麻醉医师合理使用麻醉药物有重要的指导意义。
Postoperative cognitive dysfunction（POCD）is a kind of central nervous system complication after operation and anesthesia,and the incidence rate is high in elderly patients.However,the exact mechanism of POCD remains unclear.In recent years,more and more evidence show that as one of the influencing factors of POCD,the general anesthetics may have a broad impact on cognitive function in elderly patients.The exploration of the influencing mechanism of anesthetics on POCD may have important guiding significance on the anesthesiologists＇ rational use of drugs.
出处
《中国临床医学》
2016年第3期392-395,共4页
Chinese Journal of Clinical Medicine
关键词
术后认知功能障碍
全身麻醉药
研究进展
postoperative cognitive dysfunction
general anesthetics
research progress
