摘要
自1957年硒被确认为人体所必需的微量元素以来,其具备的抗肿瘤特性被不断地证实.越来越多的研究成果显示,硒对各种肿瘤,如肝癌、乳腺癌、胃癌等,有显著地预防和抑制效果.本文对硒的发展历程、抗肿瘤机制、硒化合物抗肿瘤的研究进展进行了阐述.其中,硒抗肿瘤机制目前仍然处于假说阶段,对硒抗肿瘤的研究主要是硒化合物在动物性抗肿瘤试验、硒化合物在体外细胞抗肿瘤试验以及在临床医学上的干预性试验.
Since selenium was confirmed as an essential trace element to our human body in 1957,its anti-tumor properties have been proved by researchers continually. More and more research achievements showed the selenium could prevent and inhibit several kinds of tumors＇ growth and formation efficiently,such as liver cancer,breast cancer,and gastric cancer. The research course of the selenium,especially its study progress on its anti-tumor mechanism,was summarized in this paper. Among them,its anti- tumor mechanism remains hypothetic and selenium antitumor research is mainly on selenium compounds in animal antitumor test,selenium cell in vitro antitumor test and the interventional trials in clinical medicine.
出处
《湖北民族学院学报（自然科学版）》
CAS
2016年第2期189-194,共6页
Journal of Hubei Minzu University(Natural Science Edition)
基金
国家自然科学基金项目(21461009)
湖北省科技厅重点基金项目(2011CDA011)
2014年恩施州科技重点项目(D20140034)
关键词
硒
抗肿瘤
机制
进展
Selenium
anti-tumor
mechanism
research progress
