摘要
提出了一种利用连续Staudinger/aza-Wittig反应合成新稠环系12H,14H-喹唑啉并[3,4-a]-3,1-苯并噁嗪的方法.该方法应用叠氮化物3与三苯基膦、酰氯或CS_2的连续Staudinger/aza-Wittig/成环反应,以良好的产率生成12H,14H-喹唑啉并[3,4-a]-3,1-苯并噁嗪5或6.
A one-pot synthetic approach to new fused heterocyclic skeleton 12H,14H-quinazolino[3,4-a]-3,1-benzoxazine by Staudinger/aza-Wittig sequence has been developed. The sequential reaction of azides 3 with triphenylphosphine and acyl chlorides or CS2 produced 12H,14H-quinazolino[3,4-a]-3,1-benzoxazines 5 or 6 in good yields via a consecutive Staudinger/ aza-Wittig/cyclization reaction.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2016年第7期1662-1667,共6页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21572075)资助项目~~
