摘要
目的观察糠酸莫米松鼻喷雾剂联合鼻腔冲洗治疗变应性鼻炎(AR)的临床疗效。方法将70例AR患者分为观察组和对照组,每组35例。对照组给予糠酸莫米松鼻喷雾剂治疗,观察组在对照组基础上加用鼻腔冲洗。治疗4周后,比较两组治疗前后的临床疗效和不良反应。结果治疗后,对照组总有效率为71.43%,观察组为94.29%,两组比较差异有统计学意义(P<0.05)。两组患者鼻塞、打喷嚏、流清涕等症状明显改善,鼻内镜下体征评分有所下降,两组比较差异有统计学意义(P<0.05)。结论鼻腔冲洗联合糠酸莫米松鼻喷雾剂治疗AR,临床效果明显,不良反应小,值得临床推广应用。
Objective To compare the clinical efficacy of nasal irrigation combined with or not with Mometasone Furoate A- queous Nasal Spray in the treatment of allergic rhinitis （AR） ,and investigate the significance of nasal irrigation in the treatment of AR. Methods Totally 70 cases of AR patients were randomly divided into observation group and control group, 35 cases in each group. The control group was given the treatment of Mometasone Furoate Aqueous Nasal Spray, while the observation group was given the treatment of Mometasone Furoate Aqueous Nasal Spray and nasal irrigation. The two groups were treated for four weeks and the effects of before and after treatment in both groups were compared and adverse reactions were recorded. Results After treatment,the total effective rate of the control group was 71.43% ,that of the observation group was 94. 29%, and the difference was statistically significant （P〈0.05）. The symptoms of nasal congestion, sneezing, runny nose and so on in both groups were sig- nificantly improved,the nasal endoscopic nakedness syndrome score decreased, and the difference was statistically significant（P〈 0.05）. Conclusion Nasal irrigation combined with Mometasone Furoate Aqueous Nasal Spray has obviously clinical efficacy in the treatment of allergic rhinitis with little adverse reactions. It is worthy of further clinical application and promotion.
出处
《重庆医学》
CAS
北大核心
2016年第25期3506-3507,3513,共3页
Chongqing medicine
关键词
鼻腔冲洗
变应性鼻炎
糠酸莫米松鼻喷雾剂
疗效
nasal irrigation
allergic rhinitis
Mometasone Furoate Aqueous Nasal Spray
efficacy
