摘要
目的探讨中性粒细胞-淋巴细胞比值(NLCR)和C反应蛋白(CRP)在社区获得性肺炎(CAP)诊断和鉴别诊断中的临床价值。方法检测40例细菌性肺炎、40例支原体肺炎、40例病毒性肺炎及40例健康体检者的NLCR、白细胞总数、中性粒细胞数、淋巴细胞数和CRP含量,并对检测结果进行统计学分析。结果细菌性CAP的NLCR和CRP显著高于支原体组、病毒组和健康对照组(P<0.05)。ROC曲线分析显示,NLCR和CRP在细菌性CAP诊断中的ROC曲线下面积分别为0.911和0.896,对细菌性CAP的诊断均具有良好的敏感度和特异性。结论外周血NLCR和CRP含量对细菌性CAP的诊断和鉴别诊断有重要的临床意义。
Objective To explore the value of diagnostic and differential diagnostic with the Neutrophil-lymphocyte count ratio（NLCR）and C-reactive protein cmmunity-acquired pneumonia（CAP）.Methods The NLCR,as well as white blood cell counts,neutrophil count,lymphocyte count and the concentration of CRP were measured in 40 patients with bacterial pneumonia,40 patients with mycoplasma pneumonia,40 patients with viral pneumonia and 40 healthy subjects,and the results was analyzed by statistical methods.Results In bacterial group,the NLCR and the concentration of CRP were significantly higher than those in mycoplasma group,viral group and normal controls（P〈0.05）.According to the results of ROC curve analysis in the diagnosis of bacterial CAP,the areas of NLCR and CRP under ROC curve are 0.911 and 0.896,respectively,which have good diagnostic sensitivity and specificity.Conclusion The NLCR and CRP in peripheral blood have great significance in diagnosis and differential diagnosis of bacterial community-acquired pneumonia.
出处
《国际检验医学杂志》
CAS
2016年第18期2578-2580,共3页
International Journal of Laboratory Medicine
