摘要
目的:通过研究轻度认知功能障碍(MCI)的保护性因素,提出MCI的中医预防措施,为预防MCI提供理论依据。方法:检索Pub Med收录的研究MCI保护性因素的英文文献,将符合搜索条件的156篇文献通过人工阅读标题、摘要、全文,排除不符合纳入、排除标准的文献131篇,对符合标准的25篇文献进行MCI保护性因素的研究;根据文献研究所得的保护性因素,提出在中医"治未病"思想指导下预防MCI的措施。结果:1MCI的保护性因素有高等教育、适度饮酒、认知及社交活动、社会经济地位、体育锻炼、健康饮食、体质量指数、维生素D、血清生物利用率、内源性分泌受体、载脂蛋白2、血管紧张素转换酶抑制剂。2在"治未病"思想指导下预防MCI的措施为:饮食多蔬菜,适度摄酒;导引锻炼,疏通经络;勤于用脑,强化认知。结论:健康饮食,适度饮酒;进行体育锻炼,勤于用脑,参与认知活动,可达到预防MCI的目的。
Objective： To provide theoretical evidence for preventing mild cognitive impairment（MCI） and to recommend preventive measures of Chinese medicine, through studying protective factors of MCI. Methods： English literatures of protective factors of MCI in Pub Med were searched and 156 literatures meet the search conditions, then, through the artificial reading of titles, abstract, and the full text, 131 papers were excluded because non-compliant with the inclusion, exclusion criteria, the last 25 articles that meet the standards were studied on the protective factors of MCI. Results： 1 The protective factors were higher education, moderate alcohol consumption, cognitive activities, physical exercise, healthy diet, BMI, vitamin D, serum biological utilization, endogenous secretion, apolipoprotein 2, and angiotensin receptor inhibitors. 2 Guided by the theory of preventive treatment, methods in preventing MCI include taking more vegetables and moderate alcohol, participating physical exercise to dredging the channels, diligent with the brain, and strengthen cognitive function. Conclusion： MCI might be prevented by healthy diet and moderate alcohol, taking more physical exercises, diligent with the brain, and intensive cognition.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2016年第10期4263-4266,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家中医药管理局中医药标准化项目[No.SATCM-2015-BZ(273)]~~
关键词
轻度认知障碍
保护性因素
治未病
中医
预防
Mild cognitive impairment
Protective factors
Preventive treatment of disease
Traditional Chinese medicine
Prevention
