摘要
目的:调查我院肿瘤住院患者中药注射剂的使用情况,为规范中药注射剂在肿瘤患者中的使用提供参考。方法:回顾性分析2013–2015年使用中药注射剂的肿瘤患者病历,记录与中药注射剂相关的用药医嘱,包括药品名称、用法用量、使用时间、溶媒、联合用药、不良反应等。结果:我院肿瘤住院患者使用的四类中药注射剂中,使用频次最高的分别是康艾、生脉、丹红和痰热清注射液。抗肿瘤类中药注射剂的使用时间基本符合疗程的规定。非糖尿病肿瘤住院患者使用0.9%氯化钠注射液作为丹红注射液溶媒的比例为91.89%,生脉注射液的比例为97.37%。中药注射剂稀释后静脉滴注浓度过高的比例为86.21%。多种中药注射剂联合使用占所有中药注射剂使用病例的5.89%,记录不良反应报告15例。结论:我院中药注射剂的使用存在一些问题,包括溶媒选择不当、配置药液浓度过高、过度使用辅助用药和重复用药等,需要药师干预调整,以确保患者用药安全有效。
Objective： To investigate the usage of traditional Chinese medicine （TCM） injections used by inpatients with tumor, and provide the references for normative use of TCM injections. Methods： Retrospective analysis the medical histories of inpatients with tumor using TCM injections from 2013 to 2015, record the names of the pharmaceuticals, usage, dosage, use time, solvent, drug combination, adverse reactions, etc. Results： Among the 4 type TCM injections, Kang＇ai, Shengmai, Danhong and Tanreqing injections were most used by tumor inpatients respectively. The use time of anti-tumor TCM injections was basically in accordance with the course of treatment. The proportion of non-diabetes inpatients with tumor using 0.9% sodium chloride injection as solvent of Danhong injection was 91.89%, and that of the proportion of Shengmai injection was 97.37%. The proportion of the injected concentration of the diluted intravenous injection of TCM injection was 86.21%. The combination use of several TCM injections accounted for 5.89% of all cases using TCM injections, 15 cases of adverse reactions were reported. Conclusion： The use of TCM injection existed some problems, such as inappropriate choice of solvent, the drug concentration after configuration is too high, excessive auxiliary drug use and polypharmacy, the intervention of pharmacist is necessary so as to assure the safety of drug use in patients.
出处
《中国药物应用与监测》
CAS
2016年第5期297-299,301,共4页
Chinese Journal of Drug Application and Monitoring
基金
温州市公益性科技计划项目(Y20150374)
