摘要
目的研究老年反流性食管炎患者焦虑和抑郁心理状态及黛力新的治疗效果。方法选取我院从2014年7月至2015年12月收治的老年反流性食管炎伴焦虑抑郁患者100例,按照随机数字表法将100例老年反流性食管炎伴焦虑抑郁患者分为观察组(50例)和对照组(50例);对照组采取常规治疗,观察组在对照组的基础上合并黛力新治疗。将两组患者的汉密尔顿焦虑量表(HAMA)评分与汉密尔顿抑郁量表(HAMD)评分、反流性食管炎症状程度积分(GERDQ)数值以及临床有效率进行对比分析。结果两组患者治疗前HAMA、HAMD和GERDQ评分,组间无明显差异(P>0.05)。治疗后两组患者的HAMA、HAMD和GERDQ评分均降低(P<0.05),且观察组上述量表评分低于对照组,两组比较差异具有统计学意义(P<0.05);观察组的临床有效率(96.00%)显著高于对照组的临床有效率(82.00%),差异具有统计学意义(P<0.05)。结论黛力新辅助治疗老年返流性食管炎伴焦虑抑郁症状的患者,可显著减轻患者的焦虑抑郁症状,改善患者的临床效果,因此值得在临床推广应用。
Objective To study the psychological state of elderly patients with reflux esophagitis and the effect of Deanxit on it. Methods 100 cases of reflux esophagitis patients with anxiety and depression in our hospital were selected from July 2014 to December 2015, according to the random number table method these patients were divided into the observation group （50 cases） and the control group （50 cases）; the control group received conventional treatment, the observation group were administrated with Deanxit on the basis of the treatment of the control group .Then Hamilton Anxiety Scale （ HAMA ） score, Hamilton Depression Scale （ HAMD ） score, Gastroesophageal Reflux Disease Questionnaire （ GERDQ ） and clinical efficiency between the two groups were compared and analyzed. Results There was no significant differences of HAMA, HAMD and GERDQ scores between the two groups before treatment （P 〉 0.05 ） . After therapy, the scores of the scales above in the two groups were both lower than that before therapy, meanwhile the scores of HAMA, HAMD and GERDQ in the observation group were significantly lower than that in the control group （ P 〈 0.05 ） .The clinical effective rate of the observation group （ 96 % ） was significantly higher than that of the control group （ 82 % ）, the difference was statistically significant （ P 〈 0.05 ） . Conclusion Deanxit assisted treatment on reflux esophagitis in elderly patients with anxiety and depression can significantly improve the symptoms of anxiety and depression and the clinical effect, so it is worthy of clinical application.
出处
《国际精神病学杂志》
2016年第5期879-881,共3页
Journal Of International Psychiatry
