摘要
目的 分析重型颅脑损伤患者并发应激性溃疡的因素,为应激性溃疡的防治提供参考。方法 收集我院2010年1月~2016年2月资料齐全的231例重型颅脑损伤患者资料,其中并发应激性溃疡59例,进行单因素和多因素Logistic回归分析。结果 单因素分析显示,GCS评分低、行开颅手术、未给予肠内营养支持、空腹血糖≥8mmol/L、损伤类型中脑干损伤和弥漫性脑损伤和脑挫裂伤是并发应激性溃疡的危险因素（P〈0.05）。进一步行多因素Logistic回归分析,GCS评分3~5分、早期未给予肠内营养支持、颅脑损伤类型（脑干损伤、弥漫性脑损伤和脑挫裂伤）是并发应激性溃疡的危险因素（P〈0.05）。结论 重型颅脑损伤患者应激性溃疡发生率高,发病机制复杂,在救治时针对主要危险因素有针对性的防治。
Objective To analyze the factors of stress ulcer in patients with severe craniocerebral injury, and to guide the prevention and treatment of peptic ulcer. Methods 23l cases of severe traumatic brain injury in our hospital from January 2010 to February 2016 were selected, and 59 cases with stress ulcer were analyzed by single factor and multi factor Logistic regression analysis. Results Single factor analysis showed low GCS score, craniotomy, not of enteral nutritional support, fasting blood glucose ≥8mmol/L, injury type and diffuse brain injury brain injury and brain injury complicated with stress ulcer risk factors （P 〈 0.05）. Further multivariate Logistic regression analysis was carried on, GCS score of 3-5 points, early enteral nutritional support, the type of traumatic brain injury （brain stem injury, diffuse brain injury and brain injury） were risk factors for stress ulcer （P 〈 0.05）. Conclusion Incidence of stress ulcer in patients with severe craniocerebral injury has high and complex pathogenesis, treatment for control of major risk factors targeted.
出处
《中国医药科学》
2016年第16期141-143,共3页
China Medicine And Pharmacy
关键词
重型颅脑损伤
应激性溃疡
危险因素
Severe traumatic brain injury
Stress ulcer
Risk factors
